1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 31 (also presented at TSRC 2019)

    Impact of device variability on the determination of aldehyde compounds in e-cigarette emissions

    GILLMAN I.G.; PENNINGTON A.S.C.; HUMPHRIES K.E.
    Enthalpy Analytical, LLC, Durham NC, U.S.A.
    The determination of aldehyde compounds (formaldehyde, acetaldehyde and acrolein) in e-cigarette emissions has been widely reported in scientific literature. Recent reports have focused on the contribution of flavor compounds in e-liquids and on the ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 07 (also presented at TSRC 2019)

    HPHC analysis of seven flavors of a temperature-regulated nicotine salt-based pod system

    COOK D.(1); HIRAKI B.(1); MISRA M.(1); GILLMAN I.G.(2)
    (1) JUUL Labs, San Francisco, CA, U.S.A.; (2) Enthalpy Analytical, LLC, Richmond, VA, U.S.A.
    The JUUL Nicotine Salt Pod System (NSPS) has no user modifiable settings and is temperature regulated to minimize the generation of combustion related byproducts. Aerosol generated from NSPS pods using a cotton wicking material was evaluated for harmful ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 22 (also presented at TSRC 2019)

    Determination of primary aromatic amines in smokeless tobacco products

    CHEETHAM A.G.; MARTIN A.M.
    Enthalpy Analytical, LLC, Richmond, VA, U.S.A.
    The list of harmful and potentially harmful constituents (HPHCs) published by the FDA in 2012 features six primary aromatic amine (PAA) compounds: 1-aminonaphthalene (1-ANP), 2-aminonaphthalene (2-ANP), 4-aminobiphenyl (4-ABP), o-anisidine (o-AND), 2,6 ...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 32

    Enumeration of TBNK cells: A case for a bioanalytical assay to support clinical studies for the development of modified risk tobacco products

    NEWLAND K.; MILLER P.; FARMEN R.
    Celerion, Inc., Lincoln, NE, U.S.A.
    Smoking has been reported to lessen the body’s immune response making it more susceptible to infections. Chronic cigarette smoke exposure causes imbalance in immune homeostasis affecting the circulating immune cells. Peripheral blood lymphocytes are ...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 35 (also presented at TSRC 2019)

    Neutral red uptake (NRU) cytotoxicity analysis of aerosol generated from a temperature-regulated nicotine salt based product utilizing cotton wicking material

    COOK D.(1); HIRAKI B.(1); MISRA M.(1); GILLMAN I.G.(2)
    (1) JUUL Labs, San Francisco, CA, U.S.A.; (2) Enthalpy Analytical, LLC, Richmond, VA, U.S.A.
    The JUUL Nicotine Salt Pod System (NSPS) has no user modifiable settings and is temperature regulated to minimize the generation of combustion-related byproducts. Aerosol generated from NSPS pods using a cotton wicking material was evaluated for ...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 44 (also presented at TSRC 2019)

    In vitro testing of an ethanol collection method combining particulate and gas-vapor phase components: in vitro micronucleus assay

    SUKKA-GANESH B.; BHARTI S.K.; SCIAN M.J.; GILLMAN I.G.
    Enthalpy Analytical, LLC, Henrico, VA, U.S.A.
    Health Canada (HC) guidelines (T-502) for the collection and testing of cigarette smoke are used frequently for in vitro testing and although the guidelines allow for the collection and testing of the particulate phase (PP) and the gas-vapor (GVP) phase ...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 45 (also presented at TSRC 2019)

    In vitro testing of an ethanol collection method combining particulate and gas-vapor phase components: Bacterial Reversion Mutation (Ames) Assay

    BHARTI S.K.; SUKKA-GANESH B.; SCIAN M.J.; GILLMAN I.G.
    Enthalpy Analytical, LLC, Henrico, VA, U.S.A.
    Health Canada (HC) guidelines (T-502) for the collection and testing of cigarette smoke are used frequently for in vitro testing. Although the guidelines allow for the collection and testing of the particulate phase (PP), the gas-vapor (GVP) phase, and a ...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 46 (also presented at TSRC 2019)

    In vitro testing of an ethanol collection method combining particulate and gas-vapor phase components: neutral red assay

    SCIAN M.J.; SUKKA-GANESH B.; BHARTI S.K.; GILLMAN I.G.
    Enthalpy Analytical, LLC, Henrico, VA, U.S.A.
    The Neutral Red Uptake (NRU) assay Health Canada (HC) guidelines (T-502) for the collection and testing of cigarette smoke are used frequently for in vitro testing. Although the guidelines allow for the collection and testing of the particulate phase (PP) ...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 66 (also presented at TSRC 2019)

    Collection and characterization of mainstream cigarette smoke condensates collected using a glass fiber filter and an ethanol containing impinger

    GILLMAN I.G.; HILLDRUP J.P.; PACKETT S.R.; COLLINS J.M.
    Enthalpy Analytical, LLC, Richmond, VA, U.S.A.
    Traditional smoke collections for in vitro toxicology assays, including regulatory Health Canada (HC) testing, have utilized a multi-phase setup that traps particulate matter with a glass fiber filter followed by a liquid filled impinger for gas phase ...
  10. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 67 (also presented at TSRC 2019)

    A comparison of quartz filter collection versus electrostatic precipitation collection in e-cigarette aerosol samples

    GILLMAN I.G.; MARTIN A.M.; HOCHSTETLER S.; LATA J.; RACE N.; COLLINS D.; KELLY P.
    Enthalpy Analytical, LLC, Richmond, VA, U.S.A.
    The determination of metals in e-cigarette aerosol has been routinely performed by collecting the aerosol on quartz fiber filter pads. The trapped aerosols are digested using acid dilution and analyzed using inductively coupled plasma mass spectrometry ...