1. CORESTA Meeting, Smoke Science/Product Technology, 2011, Graz, ST 30

    Biomarkers for the smoking-related exposure to 1,3-butadiene

    ECKER J.(1); GILCH G.(1); STERZ K.(1); MARTIN C.(2); RAMSAUER B.(1); SCHERER G.(1)
    (1) ABF Analytisch-Biologisches Forschungslabor GmbH, Munich, Germany; (2) Waters GmbH, Eschborn, Germany
    1,3-butadiene is a Class 1 carcinogen ('carcinogenic to humans') according to the International Agency for Research on Cancer (IARC). This chemical is also on a WHO recommended list of toxicants in mainstream smoke of cigarettes for mandated...
  2. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 11

    An inter-laboratory comparison of urinary 3-hydroxypropylmercapturic acid measurement demonstrates good reproducibility between laboratories.

    CHEUNG F.(1); MINET E.(1); ERRINGTON G.(1); MCEWAN M.(1); SCHERER G.(2); NEWLAND K.(3); SHARIFI M.(4); BAILEY B.(5)
    (1) British American Tobacco, Group R&D, Southampton, UK; (2) ABF GmbH; (3) Celerion; (4) Labstat International Inc.; (5). Covance Laboratories Ltd.
    Background - Biomarkers have been used extensively in clinical studies to assess toxicant exposure in smokers and non-smokers and have recently been used in the evaluation of novel tobacco products. The urinary metabolite 3-HPMA, a metabolite of the...