1. CORESTA Meeting, Agronomy/Phytopathology, 2011, Santiago, AP 05

    Reduction of nornicotine in experimental burley tobaccos and impact on N-nitrosonornicotine in lamina and smoke

    HAYES A.(1); LUSSO M.(1); HAJALIGOL M.(1); LEWIS R.(2)
    (1) Altria Client Services Inc, Richmond, VA, USA; (2) North Carolina State University, Raleigh, NC, USA
    The levels and stability of nornicotine in burley tobaccos have been of considerable interest because of nornicotine's role as a primary precursor in the accumulation of N-nitrosonornicotine (NNN) during and after curing. Efforts to screen foundation...
  2. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 11

    An inter-laboratory comparison of urinary 3-hydroxypropylmercapturic acid measurement demonstrates good reproducibility between laboratories.

    CHEUNG F.(1); MINET E.(1); ERRINGTON G.(1); MCEWAN M.(1); SCHERER G.(2); NEWLAND K.(3); SHARIFI M.(4); BAILEY B.(5)
    (1) British American Tobacco, Group R&D, Southampton, UK; (2) ABF GmbH; (3) Celerion; (4) Labstat International Inc.; (5). Covance Laboratories Ltd.
    Background - Biomarkers have been used extensively in clinical studies to assess toxicant exposure in smokers and non-smokers and have recently been used in the evaluation of novel tobacco products. The urinary metabolite 3-HPMA, a metabolite of the...