1. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 22

    The statistical benefit of performing GLP bioanalysis using assays that have reduced variability

    FARMEN R.H.; NEWLAND K.E.; GRAFF D.W.; COMBS M.L.
    Celerion, Lincoln, NE, U.S.A.; Celerion, Zürich, Switzerland
    Since the tobacco industry is moving into the area of regulated bioanalysis, we have noted that there is confusion surrounding the type of regulatory standards required for analytical methods to be used for testing tobacco constituents and biomarkers in ...
  2. TSRC, Tob. Sci. Res. Conf., 2013, 67, abstr. 07

    Benzo[a]pyrene in tobacco products by ultra-pressure liquid chromatography with fluorescence detection using its deuterated analog as an internal standard.

    SODEN C.; WILLIAMSON F.
    Arista Laboratories, Inc., Richmond, VA, USA
    Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) classified by the International Agency for Research on Cancer (IARC) as a group 1 carcinogen. BaP is formed as a product of incomplete combustion and is found in tobacco smoke as well as ...
  3. TSRC, Tob. Sci. Res. Conf., 2013, 67, abstr. 34

    Development and validation of a bioanalytical assay to selectively quantitate aromatic amines (4-aminobiphenyl, o-toluidine, 1-aminonaphthalene, and 2-aminonaphthalene).

    NEWLAND K.; LAPKO V.; DZERK A.; NACHI R.
    Celerion, Lincoln, NE, USA
    new bioanalytical assay has been developed and validated that provides improved sensitivity, reproducibility, and selectivity for the analysis of total aromatic amines exposure. The determination of aromatic amines exposure has been identified as an ...