Search Results

162 results

  1. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 27

    The research and application of systematic technologies for reducing tobacco specific nitrosamines in tobacco and cigarette smoke

    BAI Ruoshi(1); ZHOU Jun(1); YANG Chunlei(2); SHI Hongzhi(3); LIU Weijuan(4); XU Tongguang(1); MA Yanjun(1); LIU Xingyu(1); YANG Jinpeng(2); WANG Jun(3); ZHANG Jie(1); YANG Zhendong(1); ZHENG Xiaoman(1); ZHANG Chen(1)
    (1) Technical Center of Beijing Cigarette Factory, Shanghai Tobacco Group Co., Ltd, Beijing, P.R. China; (2) Hubei Tobacco Research Institute, Wuhan, P.R. China; (3) Henan Agriculture University, Zhengzhou, P.R. China; (4) Yunnan Reascend Tobacco Technology (Group) Co., Ltd, Kunming, P.R. China
    Reduction of tobacco specific nitrosamines (TSNAs) in tobacco and cigarette smoke is a research hotspot. The systematic technologies for reducing TSNAs in both agricultural and industrial areas were developed and applied. The TSNA levels for the upper and ...
  2. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 28

    Effect of vacuum packaging on the formation of TSNAs in tobacco leaves during storage

    WANG Jun(1); SHI Hongzhi(1); Li Jingjing(1); ZHOU Jun(2); YANG Huijuan(1); BAI Ruoshi(2); ZHANG Chen(2)
    (1) Henan Agricultural University / China National Tobacco Cultivation & Physiology & Biochemistry Research Center / Tobacco Cultivation Key Laboratory of China Tobacco, Zhengzhou, P.R. China; (2) Beijing Cigarette Factory of Shanghai Tobacco Group Co., Ltd., Beijing, P.R. China
    Experiments were carried out to further clarify the effect of NOx on the formation of TSNAs during tobacco storage. Vacuum treatment was used to change the packing method of tobacco leaves, after which the changes of TSNAs after high temperature treatment ...
  3. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 29

    Changes in content of TSNAs and other compounds of different tobacco types during 6-year long-term storage

    ZHANG Mengyue(1); SHI Hongzhi(1); ZHOU Jun(2); DUAN Weidong(3); YANG Huijuan(1); BAI Ruoshi(2)
    (1) Henan Agricultural University, National Tobacco Cultivation & Physiology & Biochemistry Research Center, Zhengzhou, P.R. China; (2) Beijing Cigarette Factory of Shanghai Tobacco Group Co., Ltd., Beijing, P.R. China; (3) China Tobacco Henan Industrial Ltd Co., Zhengzhou, P.R. China
    Samples of flue-cured, Burley and sun-cured tobaccos from different production areas were collected to investigate the changes in content of tobacco specific nitrosamines (TSNAs) by the SPE-LC-MS/MS method during 6-year long term storage under natural ...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 13

    Release mechanism of nicotine in heat-not-burn tobacco products

    HUA Qing; ZHENG Saijing; ZHANG Wei; ZHOU Huiming; ZHANG Yichun; LU Wenjie; WU Da; SHEN Yi; LIU Baizhan
    Shanghai Tobacco Group Co., Ltd. of CNTC, Shanghai, P.R. China
    In this paper, the release of nicotine from reconstituted tobacco, on which different amounts of glycerol and water were applied, was investigated at different temperatures. The thermal release behaviour of nicotine from reconstituted tobacco was verified ...
  5. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 17

    A clinical study investigating changes in exposure to cigarette smoke chemicals in U.K. smokers who switch to using a tobacco heating product for a five-day period

    McEWAN M.(1); EBAJEMITO J.K.(1); GALE N.(1); ELDRIDGE A.(1); CAMACHO O.M.(1); MURPHY J.(1); HARDIE G.(1); PROCTOR C.J.(1)
    (1) British American Tobacco (Investments) Limited, R&D, Southampton, U.K.; (2) Celerion Inc., Lincoln, NE, U.S.A.
    Smoking is a leading cause of numerous diseases, particularly lung cancer, chronic obstructive pulmonary disease and cardiovascular diseases. Consequently, there is a recognized need to provide smokers with alternative nicotine-delivery devices that have ...
  6. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 44

    Time and spatially resolved in-situ determination of temperature, pressure and gas phase concentration of selected smoke constituents inside a burning superslim cigarette. Part I – Thermophysical mapping

    CUI Huapeng(1); EHLERT S.(2); XIE Fuwei(1); DENG Nan(1); LI Bin(1); LIU Chuan(3); McADAM K.(3); WALTE A.(2); ZIMMERMANN R.(2)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China; (2) Photonion GmbH, Schwerin, Germany; (3) British American Tobacco (Investments) Limited, Global R&D, Southampton, U.K.
    Superslim cigarettes in China are a relevant product category on the market. Accurate determination of key thermo-physical and-chemical parameters in superslim cigarettes are essential for the mechanistic understanding of combustion as well as pyrolysis ...
  7. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 59

    An inter-laboratory comparison study focused on the determination of total NNAL in human urine

    NEWLAND K.(1); SCHERER M.(2); HECHT S.S.(3); TROUDE V.(4); PRASAD G.L.(5)
    (1) Celerion Inc., Lincoln, NE, U.S.A.; (2) ABF GmbH, Planegg, Germany; (3) University of Minnesota Cancer Center, Minneapolis, MN, U.S.A.; (4) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (5) RAI Services Company, Winston-Salem, NC, U.S.A.
    In an ongoing effort to fulfil the second objective of the CORESTA Biomarker Sub-Group, periodic inter-laboratory comparison studies have been performed to evaluate the consistency of the quantitation for various harmful or potentially harmful exposure ...
  8. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 19

    Simultaneous analysis of five tobacco-specific N-nitrosamines in blood plasma of non-smokers and smokers using fully automated online solid phase extraction-liquid chromatography-tandem mass spectrometry

    ZHANG Jie(1); LIU Xingyu(1); BAI Ruoshi(1); YANG Zhendong(1); SHI Bing(2); ZHANG Chen(1); ZHOU Jun(1)
    (1) Beijing Workstation, Technology Center, Shanghai Tobacco Group Co., Ltd of CNTC, Beijing, P.R. China; (2) Army General Hospital of PLA, Beijing, P.R. China
    Tobacco-specific nitrosamines (TSNAs) in cigarette smoke are known as potential carcinogens. 4-(methylnitrosamino)-l-(3-pyridine)-l-butanol (NNAL) and its glycoside derivates are established as biomarkers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone ...
  9. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 22

    Simultaneous determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and cotinine in urine of smokers using two-dimensional liquid chromatography/tandem mass spectrometry

    LI Gang; WANG Yangzhong; TAO Liqi; WU Da; YAO Heming; LIU Baizhan
    Shanghai Tobacco Group Co., Ltd. of CNTC, Shanghai, P.R. China
    4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and cotinine are two efficient biomarkers of tobacco-specific carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and nicotine. In this contribution, we developed an effective system of two ...
  10. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 23

    Determination of 15 PAHs in mainstream cigarette smoke using concurrent solvent recondensation (CSR) injection combined with GC-MS/MS

    LUO Chen; QI Dawei; TAO Liqi; WU Bingyu; WU Da
    Technology Centre of Shanghai Tobacco Group Co., Ltd. of CNTC, Shanghai, P.R. China
    Concurrent solvent recondensation (CSR) injection technique is known as one of the approaches to fulfill large volume injection for GC. With the advantages of large volume injection, complex steps such as concentration, enrichment and solid-phase ...