Search Results

64 results

  1. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, APPOST 30

    Nicotine reduction and consumer perception: a scientific approach for quantifying possible impact of low nicotine cigarettes on consumer behaviour

    GUO Mengran(1); VERRON T.(1); DORLHAC de BORNE F.(2); PRITCHARD J.(3); COLARD S.(1)
    (1) SEITA - Imperial Brands plc, Paris, France; (2) Imperial Tobacco Limited, Leaf Research, Bergerac, France; (3) Imperial Brands, Bristol, U.K.
    In 2015, the WHO Study Group on Tobacco Product Regulation (TobReg) issued an advisory note recommending a strategy to reduce nicotine in tobacco to levels which would not be sufficient to lead to the development and/or maintenance of addiction. In the US ...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 60

    Assessing changes in biomarkers of effect in smokers who switch to a closed system electronic cigarette

    MASON L.; CAHOURS X.; O'CONNELL G.; WALELE T.
    Imperial Brands, Bristol, U.K.
    Previous studies have demonstrated that when smokers switch to an electronic cigarette, they are exposed to significantly lower levels of carcinogens and toxicants. As a result, there is a reported significant reduction in biomarkers of exposure to levels ...
  3. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 39

    The use of high content screening (HCS) in human primary lung cells to assess e-liquids of differing flavors and nicotine concentrations

    SIMMS L.(1); CZEKALA L.(1); STEVENSON M.(1); PHILLIPS G.(1); WALELE T.(2)
    (1) Imperial Brands, Bristol, U.K.; (2) Fontem Ventures, Amsterdam, The Netherlands
    Due to the current scientific debate and evolving regulatory landscape, new assays are needed to quickly determine the subtle biological response of e-liquids for both stewardship and product development purposes. For stewardship, all ingredients in the e ...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 15

    Application of an Omics approach and soft ionisation of the apolar fraction of tobacco leaf

    MASUGI E.(1); DUNKLE M.(2); MITSUI K.(1); OCHIAI N.(3); KANDA H.(3); NAGATA H.(1); DAVID F.(2); SANDRA P.(2)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Japan; (2) Research Institute for Chromatography, Kortrijk, Belgium; (3) Gerstel K.K., Tokyo, Japan
    Tobacco leaf is highly complex, containing thousands of different components that range in molecular weight and polarity. Some components can be used to characterise and differentiate leaf types using analytical techniques and data processing. In CORESTA ...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 57

    Effects of pyrolysis conditions on the formation reaction of 4-aminobiphenyl in non-isothermal pyrolysis of tobacco

    YOSHIDA S.(1,2); KOBAYASHI K.(2)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Japan; (2) Graduate School of Engineering, Yokohama National University, Yokohama, Japan
    4-Aminobiphenyl (4-ABP) is a polycyclic aromatic amine in cigarette smoke. Previous reports indicate that proteinaceous compounds (e.g. amino acids, peptides and proteins) in tobacco can highly contribute to the yield of 4-ABP measured in smoke. In a ...
  6. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPT 01

    Study on the formation mechanisms of 4-aminobiphenyl in the combustion of cigarette including isotope-labelled phenylalanine

    YOSHIDA S.(1,2); KOBAYASHI K.(2)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Japan; (2) Graduate School of Engineering, Yokohama National University, Yokohama, Japan
    Tobacco smoke is a complex mixture of a wide variety of chemical compounds, including polycyclic aromatic amines (PAAs). In past studies, it was proposed that proteins in tobacco are major precursors of PAAs. At the 2007 CORESTA SSPT Meeting (Jeju), the ...
  7. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 13

    Comparison of two pyrolysis systems in combination with gas or liquid chromatography for tobacco material

    MITSUI K.(1); DAVID F.(2); TIENPONT B.(2); OCHIAI N.(3); SASAMOTO K.(3); HIGASHI N.(1); SANDRA P.(2)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Japan; (2) Research Institute for Chromatography, Kortrijk, Belgium; (3) Gerstel K.K., Tokyo, Japan
    For the tobacco industry, the clarification of the relationship between tobacco leaf and cigarette smoke is one of the most interesting topics that has been studied for many years and various approaches and techniques have been adopted. Among these, ...
  8. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 15

    Applying a lipidomics approach for the characterisation of tobacco smoke

    YOSHIMURA Y.(1); T'KINDT R.(2); KAMIYA N.(1); MITSUI K.(1); OCHIAI N.(3); KANDA H.(3); HIGASHI N.(1); DAVID F.(2); SANDRA P.(2)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Japan; (2) Research Institute for Chromatography, Kortrijk, Belgium; (3) Gerstel K.K., Tokyo, Japan
    Lipids are considered as an important fraction in biological samples. In lipidomics, a non-target analytical approach is applied to monitor different lipid classes and to obtain detailed information on the qualitative and quantitative composition of this ...
  9. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 22

    Characterisation of tobacco leaf types using GC-MS analysis and statistical approach

    MASUGI E.(1); DUNKLE M.(2); MITSUI K.(1); OCHIAI N.(3); KANDA H.(3); HIGASHI N.(1); DAVID F.(2); SANDRA P.(2)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Japan; (2) Research Institute for Chromatography, Kortrijk, Belgium; (3) Gerstel K.K., Tokyo, Japan
    Tobacco leaf is highly complex, containing hundreds of different components that range in molecular weight and polarity, and these components can be used to characterise and differentiate leaf types using advanced analytical techniques and data processing ...