Search Results

123 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 18 (also presented at TSRC 2019)

    Comparison of a flame ionization detector (GC/FID) to a nitrogen-phosphorus detector (GC/NPD) for gas chromatographic determination of nicotine in conventional and ultra-low nicotine tobacco blends

    STINSON A.; STEELMAN D.; CLARK T.J.
    Liggett Group LLC, 100 Maple Lane Mebane NC, U.S.A.
    The established CORESTA method to determine nicotine in tobacco uses a gas chromatograph coupled with a flame ionization detector (GC/FID) (CRM 62) that uses mass spectrometry (GC/MS) (CRM 87). These methods were developed to evaluate conventional tobacco ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 32

    Enumeration of TBNK cells: A case for a bioanalytical assay to support clinical studies for the development of modified risk tobacco products

    NEWLAND K.; MILLER P.; FARMEN R.
    Celerion, Inc., Lincoln, NE, U.S.A.
    Smoking has been reported to lessen the body’s immune response making it more susceptible to infections. Chronic cigarette smoke exposure causes imbalance in immune homeostasis affecting the circulating immune cells. Peripheral blood lymphocytes are ...
  3. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 034 (also presented at CORESTA SSPT2019)

    Comparison of a flame ionization detector (GC/FID) to a nitrogen-phosphorus detector (GC/NPD) for gas chromatographic determination of nicotine in conventional and ultra-low nicotine tobacco blends

    STEELMAN D.; STINSON A.; CLARK T.J.
    Liggett Group, Mebane, NC, USA
    The established CORESTA method to determine nicotine in tobacco uses a gas chromatograph coupled with a flame ionization detector (GC/FID) (CRM 62) or that uses a mass spectrometer (GC/MS) (CRM 87). These methods were developed to evaluate conventional ...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 17

    A clinical study investigating changes in exposure to cigarette smoke chemicals in U.K. smokers who switch to using a tobacco heating product for a five-day period

    McEWAN M.(1); EBAJEMITO J.K.(1); GALE N.(1); ELDRIDGE A.(1); CAMACHO O.M.(1); MURPHY J.(1); HARDIE G.(1); PROCTOR C.J.(1)
    (1) British American Tobacco (Investments) Limited, R&D, Southampton, U.K.; (2) Celerion Inc., Lincoln, NE, U.S.A.
    Smoking is a leading cause of numerous diseases, particularly lung cancer, chronic obstructive pulmonary disease and cardiovascular diseases. Consequently, there is a recognized need to provide smokers with alternative nicotine-delivery devices that have ...
  5. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 44

    Time and spatially resolved in-situ determination of temperature, pressure and gas phase concentration of selected smoke constituents inside a burning superslim cigarette. Part I – Thermophysical mapping

    CUI Huapeng(1); EHLERT S.(2); XIE Fuwei(1); DENG Nan(1); LI Bin(1); LIU Chuan(3); McADAM K.(3); WALTE A.(2); ZIMMERMANN R.(2)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China; (2) Photonion GmbH, Schwerin, Germany; (3) British American Tobacco (Investments) Limited, Global R&D, Southampton, U.K.
    Superslim cigarettes in China are a relevant product category on the market. Accurate determination of key thermo-physical and-chemical parameters in superslim cigarettes are essential for the mechanistic understanding of combustion as well as pyrolysis ...
  6. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 59

    An inter-laboratory comparison study focused on the determination of total NNAL in human urine

    NEWLAND K.(1); SCHERER M.(2); HECHT S.S.(3); TROUDE V.(4); PRASAD G.L.(5)
    (1) Celerion Inc., Lincoln, NE, U.S.A.; (2) ABF GmbH, Planegg, Germany; (3) University of Minnesota Cancer Center, Minneapolis, MN, U.S.A.; (4) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (5) RAI Services Company, Winston-Salem, NC, U.S.A.
    In an ongoing effort to fulfil the second objective of the CORESTA Biomarker Sub-Group, periodic inter-laboratory comparison studies have been performed to evaluate the consistency of the quantitation for various harmful or potentially harmful exposure ...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 40 (also presented at TSRC 2017)

    A comparison of two different extraction methods for aromatic amines in mainstream smoke using gas chromatography-tandem mass spectrometry (GC/QQQ)

    STINSON A.(1); GILLILAND S.(1); HUCKINS A.(1); GILLMAN I.G.(2); BROWN S.S.(2); STEELMAN D.(1)
    (1) Liggett Group LLC, Mebane, NC, U.S.A.; (2) Enthalpy Analytical Inc., Durham, NC, U.S.A.
    The established GC-MS methods for the analysis of aromatic amines (o-Anisidine, o-Toluidine, 2,6-Dimethylaniline, 1-Aminonaphthalene, 2-Aminonaphthalene, and 4-Aminobiphenyl) involve complex sample preparation and analyzing the samples on a gas ...
  8. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 014

    Analysis of isotopically labeled glycerol to measure exposure from e-cigarettes

    DIBBERN E.M.; KAFONEK C.J.; BROWN G.P.; DZERK A.M.; NACHI R.; NEWLAND K.E.; ISLAM R. (presented by Erika Pfaumiller)
    Celerion, Lincoln, NE, USA
    Electronic cigarettes (ecigs) have become a popular mode of nicotine ingestion. They are often promoted as being less harmful than traditional cigarettes, but research supporting that claim is incomplete. The main chemical components of ecigs are ...
  9. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 048 (also presented at CORESTA SSPT2017)

    A comparison of two different extraction methods for aromatic amines in mainstream smoke using gas chromatography-tandem mass spectrometry (GC/QQQ)

    STINSON A.(1); GILLILAND S.(1); HUCKINS A.(1); BROWN S.S.(2); GILLMAN I.G.(2)
    (1) Liggett Group, Mebane, NC, USA; (2) Enthalpy Analytical, Durham, NC, USA
    The established GC-MS methods for the analysis of aromatic amines (o Anisidine, o Toluidine, 2, 6 Dimethylaniline, 1 Aminonaphthalene, 2 Aminonaphthalene, and 4 Aminobiphenyl) involve complex sample preparation and analyzing the samples on a gas ...