Search Results

86 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 18 (also presented at TSRC 2019)

    Comparison of a flame ionization detector (GC/FID) to a nitrogen-phosphorus detector (GC/NPD) for gas chromatographic determination of nicotine in conventional and ultra-low nicotine tobacco blends

    STINSON A.; STEELMAN D.; CLARK T.J.
    Liggett Group LLC, 100 Maple Lane Mebane NC, U.S.A.
    The established CORESTA method to determine nicotine in tobacco uses a gas chromatograph coupled with a flame ionization detector (GC/FID) (CRM 62) that uses mass spectrometry (GC/MS) (CRM 87). These methods were developed to evaluate conventional tobacco ...
  2. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 034 (also presented at CORESTA SSPT2019)

    Comparison of a flame ionization detector (GC/FID) to a nitrogen-phosphorus detector (GC/NPD) for gas chromatographic determination of nicotine in conventional and ultra-low nicotine tobacco blends

    STEELMAN D.; STINSON A.; CLARK T.J.
    Liggett Group, Mebane, NC, USA
    The established CORESTA method to determine nicotine in tobacco uses a gas chromatograph coupled with a flame ionization detector (GC/FID) (CRM 62) or that uses a mass spectrometer (GC/MS) (CRM 87). These methods were developed to evaluate conventional ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 40 (also presented at TSRC 2017)

    A comparison of two different extraction methods for aromatic amines in mainstream smoke using gas chromatography-tandem mass spectrometry (GC/QQQ)

    STINSON A.(1); GILLILAND S.(1); HUCKINS A.(1); GILLMAN I.G.(2); BROWN S.S.(2); STEELMAN D.(1)
    (1) Liggett Group LLC, Mebane, NC, U.S.A.; (2) Enthalpy Analytical Inc., Durham, NC, U.S.A.
    The established GC-MS methods for the analysis of aromatic amines (o-Anisidine, o-Toluidine, 2,6-Dimethylaniline, 1-Aminonaphthalene, 2-Aminonaphthalene, and 4-Aminobiphenyl) involve complex sample preparation and analyzing the samples on a gas ...
  4. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 048 (also presented at CORESTA SSPT2017)

    A comparison of two different extraction methods for aromatic amines in mainstream smoke using gas chromatography-tandem mass spectrometry (GC/QQQ)

    STINSON A.(1); GILLILAND S.(1); HUCKINS A.(1); BROWN S.S.(2); GILLMAN I.G.(2)
    (1) Liggett Group, Mebane, NC, USA; (2) Enthalpy Analytical, Durham, NC, USA
    The established GC-MS methods for the analysis of aromatic amines (o Anisidine, o Toluidine, 2, 6 Dimethylaniline, 1 Aminonaphthalene, 2 Aminonaphthalene, and 4 Aminobiphenyl) involve complex sample preparation and analyzing the samples on a gas ...
  5. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 057

    AKR1C1 as a biomarker for differentiating the biological effects of combustible from non-combustible tobacco products

    TRAN Q.T.(1); WOO S.(2); HENDERSON D.(2); GAO H.(3); ZACHARIAS W.(3); LIU G.(1); PRASAD G.L.(1)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Axio Research, Seattle, WA, USA; (3) University of Louisville School of Medicine, Louisville, KY, USA
    Smoking has been established as a major risk factor for developing oral squamous cell carcinoma (OSCC), but less attention has been paid to the effects of smokeless tobacco products. Our objective is to identify potential biomarkers to distinguish the ...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2015, Jeju, ST 03

    The challenges associated with emission ceilings based on multivariate quantile

    VERRON T.(2); BRY X.(1); CAHOURS X.(2); COLARD S.(2)
    (1) UM2, University Montpellier 2, France; (2) SEITA, Imperial Tobacco Group, Fleury-les-Aubrais, France
    In 2012, we evaluated and presented at the CORESTA Congress [1] the probable impact of emission ceilings as proposed by the joint working group of the WHO Study group on Tobacco Product Regulation (TobReg) [2] using experimental data and we demonstrated ...
  7. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 22

    The determination and comparison of ammonia content in tobacco products by ion chromatography and continuous flow analysis

    STINSON A.(1); GILLILAND S.(1); PAOLANTONIO A.M.(2); LOCKHART T.D.(2); GILLMAN I.G.(2)
    (1) Liggett Group LLC, Mebane, North Carolina, USA; (2) Enthalpy Analytical Inc., Durham, North Carolina, USA
    The FDA Center for Tobacco Products (CTP) has identified ammonia as a harmful or potentially harmful constituent (HPHC) in tobacco and tobacco products. However, there is currently not a single, generally accepted method for the determination of ammonia ...
  8. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 25

    The determination and comparison of hydrogen cyanide (HCN) levels in the mainstream smoke of three reference cigarettes using three different analytical techniques to understand differences and variability between methods

    STINSON A.(1); WHITEHEAD B.(1); TEWOLDE A.(1); PAOLANTONIO A.M.(2); ALVAREZ E.T.(2); GILLMAN I.G.(2)
    (1) Liggett Group LLC, Mebane, North Carolina, USA; (2) Enthalpy Analytical Inc., Durham, North Carolina, USA
    The FDA Center for Tobacco Products has identified hydrogen cyanide (HCN) as a harmful and potentially harmful constituent (HPHCs) in tobacco smoke. Currently there is no internationally accepted method for the analysis of hydrogen cyanide but at least ...
  9. CORESTA Meeting, Agronomy/Phytopathology, 2013, Brufa di Torgiano, AP 32

    Potential use of Heavy Metal Atpase (HMA) mutants to reduce cadmium translocation from root to leaf in tobacco

    JULIO E.(1); HERMAND V.(2); COTUCHEAU J.(1); DECORPS C.(1); SENTENAC C.(1); GOSTI F.(2); BERTHOMIEU P.(2); DORLHAC DE BORNE F.(1)
    (1) Imperial Tobacco Group, SEITA, Institut du Tabac, Domaine de la Tour, Bergerac, France; (2) Biochimie et Physiologie Moleculaire des Plantes - UMR5004-Montpellier SupAgro-2, Montpellier, France
    Heavy metals are naturally present in soils, or can be brought by agricultural practices or spread out by human activities. Some of them are essential for plant development. Cadmium is a non-essential heavy metal which is classified in Group 1 (= known ...
  10. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 06

    Combusted, but not smokeless tobacco product preparations, cause DNA damage in human oral cavity cells

    ZACHARIAS W.(1); GAO H.(1); PRASAD G.L.(2)
    (1) Dept. of Medicine, J.G. Brown Cancer Center, University of Louisville, Louisville, KY, USA; (2) R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA
    We examined the effects of reference tobacco preparations on DNA damage in human oral cavity cells. The oral squamous cell carcinoma cell line (101A), normal human gingival epithelial cells (HGEC), and human gingival fibroblasts (HGF) were treated with ...