Search Results

46 results

  1. CORESTA Congress, Berlin, 2016, Agronomy/Phytopathology Groups, APPOST 26

    Crop compliance: crop protection agents testing programme within purchases

    BODE L.M.; EVANS W.; INTORP M.
    Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    In order to ensure the compliance of our products, leaf grade purchases are monitored for the presence of any residual crop protection agents (CPA). CPA residue levels are first assessed for compliance against limits set by regulatory authorities and ...
  2. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 04

    Impact of different vaping machines on metal contaminations of e-cigarette aerosols

    OTTE S.; NOWAK S.; INTORP M.
    Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    The presence of trace metals in e-liquids or aerosol of electronic cigarettes (e-cigarette) has been previously reported [1]. It has also been demonstrated that contamination with tin, aluminum, copper, iron and nickel may occur from certain parts of a ...
  3. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 26

    A review of aerosol exposure systems relative to the analysis of cytotoxicity: a CORESTA In vitro Toxicity Testing Sub-Group perspective

    THORNE D.(1); WIECZOREK R.(2); FUKUSHIMA T.(3); SHIN H.J.(4); LEVERETTE R.(5); BALLANTYNE M.(6); LI X.(7); BOMBICK B.(5)
    (1) British American Tobacco, R&D Centre, Southampton, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (3) Japan Tobacco Inc., Scientific Product Assessment Centre, Yokohama, Kanagawa, Japan; (4) KT&G Corporation, Daejeon, South Korea; (5) RAI Services Company, Winston-Salem, NC, U.S.A.; (6) Covance Laboratories Ltd, Harrogate, U.K.; (7) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China
    Aerosol exposure systems offer researchers a variety of ways to customise the exposure set-up, modify experimental parameters and provide a novel and versatile platform for in vitro aerosol research. These systems produce an aerosol that more closely ...
  4. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 32

    Cellular transformation activity of different tobacco condensates in the Bhas 42 cell assay

    STEVENSON M.(1); WIECZOREK R.(2); SIMMS L.(1); PANT K.(3)
    (1) Imperial Tobacco Limited, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (3) BioReliance, Sigma-Aldrich Corp., Rockville, MD, U.S.A.
    Carcinogenesis has been described as a multi-stage process comprising of initiation, promotion and progression. Smoking is a cause of serious disease in smokers, including lung cancer. Determining the carcinogenic potential of a tobacco product ingredient ...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2015, Jeju, ST 10

    Method development and validation for the quantification of metals in liquids and aerosol of e-cigarettes

    OTTE S.; NOWAK S.; INTORP M.
    Imperial Tobacco Group, Reemtsma Cigarettenfabriken GmbH, Biological Labs Hamburg, Hamburg, Germany
    Due to the rapidly increasing popularity of e-cigarettes, several studies were carried out to characterise this new type of product. E-cigarettes produce a condensation aerosol by heating an e-liquid invariably consisting of a mixture of propylene glycol ...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2015, Jeju, ST 44

    Optimisation of in vitro standard testing of e-vapour and heated tobacco products

    WIECZOREK R.; TRELLES STICKEN E.
    Imperial Tobacco Group, Reemtsma Cigarettenfabriken GmbH, Biological Labs Hamburg, Hamburg, Germany
    The risk assessment of tobacco products includes a number of biological in vitro test assays which have become de facto standards over the last decades. These test methods are designed to assess specific toxicological end points and are able to ...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2015, Jeju, STPOST 09

    Influence of vaping topography on the retention rate of nicotine following use of e-cigarettes

    O’CONNELL G.(1); BURSEG K.(2); BREIEV K.(3); BIEL S.S.(2); CAHOURS X.(4); COLARD S.(1,4)
    (1) Imperial Tobacco Group, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH, Imperial Tobacco Group, Hamburg, Germany; (3) IONICON Analytik GmbH, Innsbruck, Austria; (4) SEITA, Imperial Tobacco Group, Fleury-les-Aubrais, France
    The “quantity of nicotine exhaled” by an e-cigarette user is the most important factor influencing bystander exposure to nicotine. To that end, it is important to determine the quantity of nicotine that is retained by the e-cigarette user and not exhaled. ...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2015, Jeju, STPOST 14

    Use of the TK6 human lymphoblastoid cell line for the assessment of the genotoxic potential of complex mixtures

    TRELLES STICKEN E.; WIECZOREK R.
    Imperial Tobacco Group, Reemtsma Cigarettenfabriken GmbH, Biological Labs Hamburg, Hamburg, Germany
    There has been a significant focus over recent years to evaluate the relevance of in vitro micronucleus (IVM) data obtained with cell lines of different origin and different status regarding the p53 checkpoint. Those evaluations and additional ...
  9. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 11

    Investigations on cigar burning and yields under different smoking intensities

    MUELLER C.(1); COLARD S.(2)
    (1) Imperial Tobacco Group, Reemtsma Cigarettenfabriken GmbH, Hamburg, Germany; (2) Imperial Tobacco Ltd, Bristol, U.K.
    In order to better understand the effect of smoking parameters on the cigar burning process and mainstream smoke yields, a pilot study was conducted. A ‘large’ commercial cigar (weight about 6.5 g) was investigated for the generation of ‘tar’, nicotine, ...
  10. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 80

    The CORESTA recommended in vitro test battery alongside the National Research Council vision for toxicity testing in the 21st Century

    SIMMS L.(1); WIECZOREK R.(2); TRELLES STICKEN E.(2)
    (1) Imperial Tobacco Ltd, Bristol, U.K.; (2) Imperial Tobacco Group, Reemtsma Cigarettenfabriken GmbH, Biological Labs Hamburg, Hamburg, Germany
    The CORESTA In vitro Toxicity Testing of Tobacco Smoke Task Force recommended a test battery in 2004 which has been subsequently used by the tobacco industry. A similar in vitro test battery has been used by the International Community on Harmonisation ...