Search Results

174 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 52

    Changes in TSNA contents and sensory quality of ultra-low nicotine tobacco leaves produced by grafting with eggplant

    REN Mengjuan(1); SHI Hongzhi(1); LI Hongliang(2); ZHOU Jun(3); TANG Chaoqi(3); BAI Ruoshi(3); ZHANG Mengyue(1)
    (1) College of Tobacco Science of Henan Agricultural University / Tobacco Cultivation Key Laboratory of China Tobacco / Tobacco Harm Reduction Research Center of HAU, Zhengzhou, P.R. China; (2) Xuchang Tobacco Company of Henan, P.R. China; (3) Shanghai Tobacco (Group) Co., Ltd., Shanghai, P.R. China
    Ultra-low nicotine tobacco production has been given broad attention due to the possible regulation of nicotine content in cigarette tobacco. Based on grafting with eggplant (eggplant as rootstock, flue-cured variety Yunyan 87 as scion), the feeding...
  2. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, APPOST 02

    Effects of spraying exogenous glycerol and molybdate on nitrate accumulation in pot-grown Burley tobacco leaves

    FENG Yuqing(1); SHI Hongzhi(1); LI Yafei(1,2); ZHOU Jun(3)
    (1) College of Tobacco Science of Henan Agricultural University, Tobacco Harm Reduction Research Center, Zhengzhou, P.R. China; (2) Henan Institute of Economics and Trade, Zhengzhou, P.R. China; (3) Beijing Cigarette Factory, Shanghai Tobacco Group Co., Ltd., Beijing, P.R. China
    Burley tobacco is well known as yellow-green leaf tobacco with reduced chlorophyll content and lower carbohydrate accumulation and lower nitrogen assimilation ability, resulting in the accumulation of nitrate, one of the precursors of TSNAs....
  3. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, APPOST 10

    The influence of sodium carbonate buffer on TSNAs accumulation and leaf quality during tobacco storage

    LIU Xingyu(1); LIU Deshui(1); MA Li(1); MA Yanjun(1); YANG Zhendong(1); ZHANG Jie(1); LIN Lin(2); BAI Ruoshi(1); ZHOU Jun(1)
    (1) Technology Center, Shanghai Tobacco Group Co., Ltd., Beijing, P.R. China; (2) Beijing Tobacco Quality Supervision and Testing Station, Beijing, P.R. China
    Storage of tobacco leaves is an important stage in tobacco processing. Tobacco Specific N-nitrosamines (TSNAs) in tobacco leaves gradually increase during storage. The purpose of this study was to investigate the influence of sodium carbonate on the...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 28

    Simultaneous determination of 20 amino acids in tobacco leaves by multiple heart-cut two-dimensional liquid chromatography

    WANG Yangzhong; QI Dawei; WU Da; LIU Baizhan
    Technology Center, Shanghai Tobacco Group Co., Ltd., Shanghai, P.R. China
    Amino acids are important aroma precursors in tobacco. They can react with reducing sugar in the processes of tobacco curing, aging or smoking, which is called the Maillard reaction. Various heterocyclic aroma compounds are generated in this...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 44

    Lung biomarkers of harm/effect for tobacco regulatory research: opportunities and challenges – a literature review

    MAKENA P.(1); EDMISTON J.(2); BEATTIE E.(3); MASON E.(4); McEWAN M.(5); PRASAD K.(5)
    (1) RAI Services Company, Winston-Salem, NC, U.S.A.; (2) Altria Client Services LLC, Richmond, VA, U.S.A.; (3) Cliantha Research Limited, Canada; (4) Imperial Brands PLC, Bristol, U.K.; (5) British American Tobacco (Investments) Limited, Southampton, U.K.
    Biomarkers of potential harm (BoPH) are indicators of biological perturbations in response to smoking, which may contribute to smoking-related disease. In this review, a project of the CORESTA Biomarkers Sub-Group, we critically assessed the...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 45

    Meta-analysis of two biomarkers of exposure of tobacco products

    AYALA-FIERRO F.(1); ELAMIN A.(2); FROST-PINEDA K.(3); JIN T.(3); PRASAD G.L.(3); SARKAR M.(4); SCHMIDT E.(3); VERRON T.(5)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (3) RAI Services Company, Winston-Salem, NC, U.S.A.; (4) Altria Client Services LLC, Richmond, VA, U.S.A.; (5) SEITA - Imperial Brands, Paris, France
    In the context of tobacco products, broadly two types of biomarkers exist, biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH). BoE measure exposure to tobacco constituents, e.g. carbon monoxide (CO) and nicotine equivalents (NEQs)....
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 46

    Analysis of aroma components in oral fluids of cigarette smokers

    FEI Ting; BI Yanjiu; LIANG Demin; QI Dawei; TAO Liqi; YU Jie; WU Da; LIU Baizhan
    Technology Center, Shanghai Tobacco Group Co., Ltd., Shanghai, P.R. China
    The sensory quality of cigarettes depends on the effects of chemical components in the mainstream smoke on the consumer’s sensory organs. To provide a reference for cigarette quality assessment, a method for analysing aroma components in the oral...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 56

    Effects of acidic components in cigarette smoke on lipid metabolism in salivary glands of rats

    SHA Yunfei; LIANG Demin; WU Da; LIU Baizhan
    Technology Center, Shanghai Tobacco Group Co., Ltd., Shanghai, P.R. China
    Some components in tobacco, such as acidic components, stimulate the salivary secretion in smokers. However, their effect on lipid metabolism in salivary gland tissues remains unclear. In this study, the effects of acidic components in cigarette...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 42

    Characterization of whole mainstream smoke/aerosol delivery within the Vitrocell® Ames 48 high throughput exposure module using different tobacco product types

    LEVERETTE R.(1); KEYSER B.(1); SEYMOUR A.(2); HOLLINGS M.(2)
    (1) RAI Services Company, Scientific & Regulatory Affairs, Winston-Salem, NC, U.S.A.; (2) Covance Laboratories Ltd, Otley Road, Harrogate, North Yorkshire, U.K.
    The preferred means of assessing combustible or other aerosol-generating tobacco products in vitro is by direct exposure of cell cultures to freshly generated whole mainstream smoke/aerosols. This approach eliminates the fractionation of...
  10. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 49

    The CORESTA in vitro test battery for combustible tobacco products: update from the 2004 Rationale and Strategy Report

    LEE K.M.(1); JORDAN K.G.(2); WIECZOREK R.(3); MOENNIKES O.(4); CLEMENTS J.(5); CROOKS I.(6); HASHIZUME T.(7); MILLER J.(8); WEBER E.(9); YOSHINO K.(7)
    (1) Altria Client Services, Richmond, VA, U.S.A.; (2) RAI Services Company, Winston-Salem, NC, U.S.A.; (3) Imperial Brands, Reemtsma Cigarettenfabriken GmbH, Hamburg, Germany; (4) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (5) Covance Laboratories Ltd, Harrogate, U.K.; (6) British American Tobacco (Investments) Ltd, R&D, Southampton, U.K.; (7) Japan Tobacco Inc., Yokohama, Kanagawa, Japan; (8) JT International SA, Geneva, Switzerland; (9) Ökolab, Vienna, Austria
    In 2004, the CORESTA In Vitro Toxicity Task Force issued a rationale and strategy report, commonly known as “the CORESTA in vitro test battery guideline”. The goals of this guideline were to: 1) develop the rationale and strategy for conducting in...