Search Results

138 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 12

    Review of current methodologies in evaluating abuse liability of nicotine and tobacco products in the U.S. regulatory environment

    EVANS S.(1); KONG M.C.(2); CAMPBELL L.(2); SHERWOOD N.(3); PRASAD K.(4)
    (1) Turning Point Brands, Louisville, KY, U.S.A.; (2) Altasciences Clinical Research, Laval, Canada; (3) Neil Sherwood Consulting, Nyon, Switzerland; (4) British American Tobacco, R&D, Millbrook, Southampton, U.K.
    Traditional definitions of abuse and misuse do not apply to a consumer product such as tobacco that consumers essentially use ‘as intended’. In contrast to pharmaceutical products, a guidance for abuse liability testing of nicotine and tobacco...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 52 (also presented at TSRC 2019)

    Application of differential ion mobility spectrometry-tandem mass spectrometry for improved assay selectivity and sensitivity in the quantitation of tobacco biomarkers NNN, NNAL and 2-/3-HPMA in human urine

    PLOMLEY J.B.
    Altasciences, Laval, QC, Canada
    Differential ion mobility spectrometry (DMS) has recently emerged as an orthogonal gas-phase ion separation technique which, when interfaced between liquid chromatography (LC) and tandem mass spectrometry (MS/MS), promises improvements in both assay...
  3. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 044

    Abuse liability of very low nicotine content cigarettes with characterization of nicotine exposure profiles in adult smokers

    LEVY-COOPERMAN N.(1); SHRAM M.J.(1); KELSH D.(2); VINCE B.(2); CARMINES E.(3)
    (1) Altreos Research Partners, Toronto, ON, Canada; (2) Altasciences/Vince and Associates, Overland Park, KS, USA; (3) Carmines Consulting, Scottsdale, AZ, USA
    Objectives: In 2017, FDA announced the intention to explore limiting nicotine in cigarettes to minimal/non-addictive levels. Research indicates that reduced nicotine content would potentially limit reinforcing effects of cigarettes. We conducted 2...
  4. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 102 (also presented at CORESTA SSPT2019)

    Novel application of differential ion mobility spectrometry-tandem mass spectrometry for improved assay selectivity and sensitivity in the quantitative determination of total NNN total NNAL and 2- / 3-HPMA in human urine

    PLOMLEY J.
    Altasciences, Laval, Canada
    Differential Ion Mobility Spectrometry (DMS) has recently emerged as an orthogonal gas-phase ion separation technique which, when interfaced between liquid chromatography (LC) and Tandem Mass Spectrometry (MS/MS), promises improvements in both assay...
  5. CORESTA Meeting, Agronomy/Phytopathology, 2013, Brufa di Torgiano, APPOST 01

    Performance of fire-cured tobacco with compost from urban sources

    COZZOLINO E.; LEONE V.; LOMBARDI P.
    Consiglio per la Ricerca e la Sperimentazione in Agricoltura - Unità di Ricerca per le Colture Alternative al Tabacco (CRA-CAT), Scafati (SA), Italy
    A two-year trial of Kentucky fire-cured tobacco fertilisation with compost from urban organic waste was conducted with three cultivars (Foiano, Riccio beneventano and SKL) on two farms in the province of Benevento (Italy). A commercial compost,...
  6. CORESTA Meeting, Agronomy/Phytopathology, 2013, Brufa di Torgiano, APPOST 04

    Influence of plant density and leaf priming collection on seed and seed oil yield in tobacco

    BUCCIARELLI S.(1); CIVITELLA D.(1); FECONDO G.(1); GHIANNI G.(1); SORRENTINO C.(2); DEL PIANO L.(2); RAIMO F.(2); STANISCI V.(3)
    (1) Consorzio per la Divulgazione e la Sperimentazione delle Tecniche Irrigue (CO.T.IR), Vasto (CH), Italy; (2) Consiglio per la Ricerca e la Sperimentazione in Agricoltura - Unità di Ricerca per le Colture Alternative al Tabacco (CRA-CAT), Scafati (SA), Italy; (3) ECOFOX, Vasto (CH), Italy
    In the EU the Common Agricultural Policy (CAP) reform of 2004 has established a gradual reduction in incentives for the production of tobacco. In Italy there was a reduction of about 30% of the area under tobacco cultivation from 2000 to 2010....
  7. CORESTA Meeting, Agronomy/Phytopathology, 2013, Brufa di Torgiano, APPOST 05

    New cultivars for the Italian Burley industry

    COZZOLINO E.; LEONE V.; LOMBARDI P.
    Consiglio per la Ricerca e la Sperimentazione in Agricoltura - Unità di Ricerca per le Colture Alternative al Tabacco (CRA-CAT), Scafati (SA), Italy
    Lack of information about cultivar adaptation to specific areas is a hindrance to the progress of the tobacco industry. To provide such information for Italian Burley areas, an on-farm variety trial is underway at Vitulazio, in the province of...
  8. CORESTA Meeting, Agronomy/Phytopathology, 2013, Brufa di Torgiano, APPOST 08

    SSR analysis of genetic polymorphism in a Nicotiana Germplasm Collection

    DEL PIANO L.; DI DATO F.; ABET M.; RAIMO F.; SORRENTINO C.; SICIGNANO M.; ENOTRIO T.
    Consiglio per la Ricerca e la Sperimentazione in Agricoltura - Unità di Ricerca per le Colture Alternative al Tabacco (CRA-CAT), Scafati (SA), Italy
    Tobacco (Nicotiana tabacum L.) is an important agricultural crop plant that plays a significant role in the economies of many countries. Tobacco breeding aims to develop varieties with wide adaptability, higher potential and suitable chemical...