Search Results

57 results

  1. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 38

    Impact of cigarette paper parameters on smoke yields of cigarettes with different circumferences

    MÜLLER P.; GLEINSER M.; BACHMANN S.; VOLGGER D.
    Papierfabrik Wattens GmbH & Co. KG, Wattens, Austria
    Cigarettes with reduced circumference are very popular in several markets. Over the last decade a significant growth rate has been observed worldwide. Changing the circumference has an influence on the physical properties of the unlit cigarette...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 62

    Immune functions are perturbed to a greater extent with smoking rather than moist snuff use

    TRAN Q.T.(1); ARIMILLI S.(2); JOHNSON E.(3); LIU Gang(1); PRASAD G.L.(1)
    (1) RAI Services Company, Winston-Salem, NC, U.S.A.; (2) Wake Forest University, School of Medicine, Department of Microbiology and Immunology, Winston-Salem, NC, U.S.A.; (3) University of North Carolina, Department of Mathematics and Statistics, Greensboro, NC, U.S.A.
    Cigarette smoking is a major risk factor for lung cancer, chronic obstructive pulmonary disease, and cardiovascular disease (CVD). Existing epidemiological data suggest moist snuff consumption is generally associated with reduced health risks...
  3. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 066

    Distinct gene expression changes in peripheral blood mononuclear cells exposed to combustible versus non-combustible tobacco product preparations

    TRAN N.Q.(1); ARIMILLI S.(2); MADAHIAN B.(3); HOMAYOUNI R.(3); PRASAD G.L.(1)
    (1) RAI Services, Winston-Salem, NC, USA; (2) Wake Forest University, Winston-Salem, NC, USA; (3) Quire Inc., Memphis, TN, USA
    Cigarette smoking exerts diverse physiological effects including immune suppression. Existing epidemiological data show that consumption of smokeless tobacco products, such as moist snuff, is less harmful relative to smoking. We previously...
  4. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 080

    Differential gene expression and functional responses in peripheral blood mononuclear cells pretreated with combustible and non-combustible tobacco products

    TRAN Q.T.(1); ARIMILLI S.(2); LIU Gang(1); MAKENA P.(1); PRASAD G.L.(1)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Wake Forest School of Medicine, Winston-Salem, NC, USA
    Chronic smoking is known to alter immune responses, which compromises tumor surveillance and host defense against microbial infections. We previously showed that smokers (SMK) exhibit distinct peripheral blood mononuclear cell (PBMC) gene expression...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 53 (also presented at TSRC 2017)

    Fumex: light scattering sensor for the analysis of electronic cigarette aerosols

    WANG Q.(1); LI W.(2); LIPOWICZ P.(2); DUNKHORST W.(3); KOCH W.(3)
    (1) Eurofins Lancaster Laboratories, c/o Altria Client Services LLC, Research, Development and Regulatory Affairs, Richmond, VA, U.S.A.; (2) Altria Client Services LLC, Research, Development and Regulatory Affairs, Richmond, VA, U.S.A.; (3) Fraunhofer ITEM, Department of Aerosol Technology, Hannover, Germany
    A new sensor based on light scattering has been designed to perform highly time resolved measurements of the mass concentration and the mass median diameter (MMD) of aerosols formed in e-cigarettes. Aerosols generated in e-cigarettes are spherical,...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 19

    Combustible and smokeless tobacco product preparations differentially regulate calcium mobilization in the human leukemic HL60 cell line

    MAKENA P.(2); ARIMILLI S.(1); DAMRATOSKI B.E.(1); PRASAD G.L.(2)
    (1) Wake Forest University School of Medicine, Department of Microbiology & Immunology, Winston-Salem, NC, U.S.A.; (2) RAI Services Co., Winston-Salem, NC 27102, U.S.A.
    Increased calcium (Ca2+) mobilization is central to leukocyte signaling and for regulation of immune responses. Although evidence suggests that cigarette smoking affects several biological functions including inflammatory responses, how the use of...
  7. CORESTA Congress, Berlin, 2016, Agronomy/Phytopathology Groups, AP 16

    Role of polyamines in leaf ripening of low alkaloid tobacco varieties

    NÖLKE G.(1); VOLKE D.(1); CHUDOBOVA I.(1); HOUDELET M.(1); LUSSO M.(2); FREDERICK J.(2); WAREK U.(2); STRICKLAND J.(2); XU D.(2); FISCHER R.(1); SCHINKEL H.(1); SCHILLBERG S.(1)
    (1) Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Aachen, Germany; (2) Altria Client Services LLC, Research, Development and Regulatory Affairs, Richmond, VA, U.S.A.
    Traditional breeding and molecular approaches have been used to develop tobacco varieties with reduced nicotine and secondary alkaloid levels. However, low-alkaloid (LA) tobacco varieties often show impaired leaf ripening and senescence leading to...
  8. CORESTA Congress, Berlin, 2016, Agronomy/Phytopathology Groups, AP 25

    Sucker control through biotechnology

    XU D.(1); GRUNDMANN L.(2); SHEN Y.(1); NOLL G.(2); YANG J.(1); KUDITHIPUDI C.(1); FREDERICK J.(1); PRUEFER D.(2); WAREK U.(1); STRICKLAND J.(1)
    (1) Altria Client Services LLC, Research, Development and Regulatory Affairs, Richmond, VA, U.S.A.; (2) Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Muenster, Germany
    Tobacco plants exhibit strong apical dominance that effectively inhibits axillary bud development. However, upon shoot apical meristem removal (topping), loss of apical dominance quickly allows axillary buds to grow (suckers) resulting in yield loss...