1. CORESTA Congress, Paris, 2006, IG 02

    Functional characterization of the nicotine N-demethylase gene of tobacco

    DEWEY R.E.; SIMINSZKY B.; BOWEN S.W.; GAVILANO L.; WAREK U.; HAYES A.
    North Carolina State University, Dept. of Crop Science, Raleigh, NC, USA; University of Kentucky, Dept. of Plant and Soil Sci., Lexington, KY, USA; Philip Morris USA, Richmond, VA, USA
    In tobacco, nicotine is metabolized to nornicotine via the activity of the nicotine N-demethylase enzyme. During the curing and processing of the leaf, nornicotine serves are the direct precursor in the synthesis of N-nitrosonornicotine (NNN), a tobacco ...