Search Results

548 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 50

    Reducing nicotine in Burley tobacco by combining low alkaloid varieties and agronomic practices

    FISHER A.M.; FISHER C.R.; JI H.
    University of Kentucky, Lexington, KY, U.S.A.
    The United States Food and Drug Administration (FDA) has requested comments on a possible nicotine standard of 0.3-0.5 mg/g in tobacco filler. There are currently no publicly available varieties that approach this level. The objective of this study was to ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 53

    NNN – a suitable biomarker of exposure from smoke and new nicotine delivery products?

    PLUYM N.; TAUCHER J.; SCHERER G.; SCHERER M.
    ABF Analytisch-Biologisches Forschungslabor GmbH, Planegg, Germany
    N-Nitrosonornicotine (NNN) is believed to play a critical role in the development of cancer in tobacco users and was therefore classified by the International Agency for Research on Cancer (IARC) as a Group 1 carcinogen. Hence, urinary NNN is commonly ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 54

    Clinical biomarkers of compliance for use in potentially reduced-risk product switching studies

    McEWAN M.(1); GALE N.(1); HARDIE G.(1); SCHERER M.(2); PLUYM N.(2); EBAJEMITO J.K.(1); CAMACHO O.M.(1); GRIFFITHS A.(1); PROCTOR C.J.(1)
    (1) British American Tobacco (Investments) Limited, Research and Development, Southampton, U.K.; (2) ABF GmbH, Planegg, Germany
    Preclinical assessments and clinical studies have shown significant reductions in toxicants in tobacco heating product (THP) aerosols compared to smoke from conventional cigarettes. Further studies to assess if these toxicant reductions translate to ...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 13

    Analysis of propylene oxide and glycidol in tobacco smoke and e-cigarette vapour

    LANDMESSER A.; SCHERER G.; PLUYM N.; SCHERER M.
    ABF Analytisch-Biologisches Forschungslabor GmbH, Planegg, Germany
    We recently performed a clinical study with e-cigarette users (vapers) and smokers. The stable-isotope labeled e-cigarette constituents propylene glycol, glycerol, and nicotine in the test e-cigarette were used in order to investigate the e-cigarette ...
  5. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 052

    Relationship of alkaloids, PON, TSNAs, nitrate and nitrite: a two-year field analysis

    WU YING; JI HUIHUA; JACK FISHER A.; FANNIN F.; CHATTOPADHYAY N.; BUSH L.
    University of Kentucky, Lexington, KY, USA
    Tobacco-specific nitrosamines (TSNAs) are a class of nitrosamines that are included in the FDA’s Harmful and Potentially Harmful Constituents (HPHC) list. Two of these, Nʹ-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ...
  6. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 101

    Characterization of the bacterial community associated with smokeless tobacco reference products under different storage conditions

    LIU SHUANG; GREENHUT I.; MOE L.
    University of Kentucky, Lexington, KY, USA
    In this study we characterize the bacterial communities associated with smokeless tobacco reference products (STRP), including loose leaf chewing tobacco (3S1), moist snuff (3S3), American snus (1S5), and Swedish snus (1S4) during a 1-year storage period. ...