1. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 88

    Quantitative determination of enantiomers of tobacco-specific nitrosamines in tobacco using gas chromatography-mass spectrometry

    JI H.(1); FANNIN F.(2); CAI B.(2); BUSH L.P.(2)
    (1) University of Kentucky, Kentucky Tobacco Research and Development Center, Lexington, KY, U.S.A.; (2) University of Kentucky, Department of Plant and Soil Sciences, Lexington, KY, U.S.A.
    Different enantiomers of tobacco-specific nitrosamines (TSNAs) have different biological activities. TSNAs exist as either (R)- or (S)-enantiomeric isoforms that differ at the 2'-C position of the pyrrolidine ring. It has been reported that (S)-N& ...