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262 results

  1. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 01 (also presented at TSRC 2018)

    FDA advance notice of proposed rulemaking for nicotine level of combusted cigarettes – feasibility for compliance via tobacco plant genetics?

    HIATT E.
    R.J. Reynolds Tobacco Co., Winston-Salem, NC, U.S.A.
    On March 16, 2018, the U.S. Food and Drug Administration (FDA) published an advance notice of proposed rulemaking (ANPRM) entitled “Tobacco Product Standard for Nicotine Level of Combusted Cigarettes.” The publication of an ANPRM solicits information and ...
  2. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 006

    Qualitative assessment of flavor ingredients in market electronic nicotine delivery systems

    HUDSON A.G.(1); CULBERT C.G.(2)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA; (2) RAI Services Company, Winston-Salem, NC, USA
    As the use of electronic nicotine delivery systems (ENDS) grows, it may be useful to understand the types of flavor compounds that are being added as ingredients to the ENDS currently available on the market. A qualitative analysis of flavor compounds was ...
  3. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 013

    Method development for pH analysis of ends aerosol and e-liquid

    HEFNER T.(1); ST. CHARLES F.K.(2); ANDERSON J.(3)
    (1) R.J. Reynolds Tobacco Company, Winston Salem, NC, USA; (2) St.Charles Consultancy, Winston Salem, NC, USA; (3) Eurofins Lancaster Labs, Winston Salem, NC, USA
    E-liquids are hygroscopic, non-aqueous liquids containing a small amount of water (~3-15%). When the pH of a non-aqueous liquid is measured using conventional methods and calibration buffers, the value can only be regarded as an "apparent pH". ...
  4. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 017

    Development of a 3D human oral tissue model for oral permeation of smokeless moist snuff

    KEYSER B.(1); ROWE J.(2); WEIDMAN R.(2); FIELDS W.(1)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Tobacco product use is a risk factor in the development of oral cancer, although epidemiology studies show this risk is far less with smokeless tobacco product use than cigarette smoking. While smokeless tobacco contains harmful and potentially harmful ...
  5. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 022

    Thermal profiling methods for the evaluation of electronic nicotine delivery systems (ENDS)

    ROGERS R.(1); SZABO D.T.(1); STRASSER J.(1); REYNOLDS C.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Electronic nicotine delivery systems (ENDS) contain tobacco-derived nicotine formulated in a liquid (“e-liquid”) typically consisting of glycerin, propylene glycol, water and flavoring ingredients. The e-liquid is aerosolized via a heating element in the ...
  6. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 072 (also presented at CORESTA 2018)

    FDA advance notice of proposed rulemaking for nicotine level of combusted cigarettes – feasibility for compliance via tobacco plant genetics?

    HIATT E.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    On March 16, 2018, the U.S. Food and Drug Administration (FDA) published an advance notice of proposed rulemaking (ANPRM) entitled “Tobacco Product Standard for Nicotine Level of Combusted Cigarettes.” The publication of an ANPRM solicits information and ...
  7. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 081

    Determination of the levels of short chain organic acids in tobacco and liquids used in electronic cigarettes

    MOLDOVEANU S.; KILBY K.B.; HUDSON A.G.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Short chain organic acids from acetic to caprylic play an important role in tobacco flavor, and may be present in the flavors added to the liquids used in electronic smoking devices (e-liquids). For this reason, the determination of the level of those ...
  8. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 085

    Survey of carbonyls in aerosols from electronic nicotine delivery systems

    CULBERT C.G.(1); WEIDMAN R.A.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Due to the growth of the electronic nicotine delivery systems (ENDS) category and the potential role of ENDS in switching and cessation from traditional combustible cigarettes, there is increased interest in the relative yields of harmful and potentially ...