Search Results

58 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 47

    Identification, discussion and recommendations for the optimal generation and use of in vitro genotoxicity assay data for tobacco and nicotine products

    DESAI P.(1); CURREN R.(1); MOORE M.M.(2)
    (1) Institute for In Vitro Sciences, Gaithersburg, MD, U.S.A.; (2) Ramboll Environ Inc., Little Rock, AR, U.S.A.
    The Institute for In Vitro Sciences is sponsoring a series of workshops to identify, discuss and develop recommendations for optimal scientific/technical approaches for utilizing in vitro regulatory genotoxicity assay data within and across tobacco and ...
  2. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 008

    Workshop series to identify, discuss and develop recommendations for the optimal generation and use of in vitro genotoxicity assay data for tobacco and nicotine products

    MOORE M.M.(1); CURREN R.(2)
    (1) Ramboll US Corporation, Little Rock, AR, USA; (2) Institute for In Vitro Sciences, Gaithersburg, MD, USA
    The Institute for In Vitro Sciences is sponsoring a series of workshops to identify, discuss and develop recommendations for optimal scientific/technical approaches for utilizing in vitro regulatory genotoxicity assay data within and across tobacco and ...
  3. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 097

    Methodology to determine the particle size distribution, mean, and standard deviation from sieve data

    ST. CHARLES F.K.(1); MORGAN W.T.(2)
    (1) St. Charles Consultancy, Lewisville, NC, USA; (2) RAI Services, Winston-Salem, NC, USA
    A method is described which allows the mean and standard deviation of particle size to be estimated from sieve data. The results can be used to calculate and plot the particle size distribution, the cumulative distribution, percentiles, and guide sieve ...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 35

    Different population modeling approaches lead to directionally similar conclusions about the potential for tobacco harm reduction

    BACHAND A.(1); SULSKY S.(1); CURTIN G.(2)
    (1) Ramboll U.S. Corp., Amherst, MA, U.S.A.; (2) RAI Services Co., Winston-Salem, NC, U.S.A.
    There are a number of dynamic population models that can be used to quantify the overall population health effects of beneficial and/or harmful changes in tobacco use patterns. These models can be broadly categorized as either following a single birth ...
  5. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 36 (also presented at TSRC 2018)

    Multi-dimensional tipping point analyses: Assessing simultaneous shifts in tobacco use patterns from a higher to a lower risk product

    BACHAND A.(1); SULSKY S.(1); CURTIN G.(2)
    (1) Ramboll U.S. Corp., Amherst, MA, U.S.A.; (2) RAI Services Co., Winston-Salem, NC, U.S.A.
    The Dynamic Population Modeler (DPM(+1)) employs a birth cohort framework to estimate effects on population mortality if tobacco use patterns shift from a higher- to lower-risk product. DPM(+1) allows for evaluation of changes in use patterns within the ...
  6. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 013

    Method development for pH analysis of ends aerosol and e-liquid

    HEFNER T.(1); ST. CHARLES F.K.(2); ANDERSON J.(3)
    (1) R.J. Reynolds Tobacco Company, Winston Salem, NC, USA; (2) St.Charles Consultancy, Winston Salem, NC, USA; (3) Eurofins Lancaster Labs, Winston Salem, NC, USA
    E-liquids are hygroscopic, non-aqueous liquids containing a small amount of water (~3-15%). When the pH of a non-aqueous liquid is measured using conventional methods and calibration buffers, the value can only be regarded as an "apparent pH". ...
  7. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 037 (also presented at CORESTA 2018)

    Multi-dimensional tipping point analyses: assessing simultaneous shifts in tobacco use patterns from a higher to a lower risk product

    CURTIN G.M.(1); BACHAND A.(2); SULSKY S.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Ramboll US Corporation, Amherst, MA, USA
    The Dynamic Population Modeler (DPM(+1)) employs a birth cohort framework to estimate effects on population mortality if tobacco use patterns shift from a higher- to lower-risk product. DPM(+1) allows for evaluation of changes in use patterns within the ...
  8. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 076

    Do levels of menthol in mainstream cigarette smoke influence dependence? Data from NHANES 2007-2014

    PARMS T.(1); VAN LANDINGHAM C.(2); MARANO K.M.(1)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Ramboll, Monroe, LA, USA
    A 2013 preliminary scientific evaluation by the U.S. Food and Drug Administration (FDA) concluded that menthol in cigarettes is likely associated with increased initiation and progression to regular cigarette smoking, increased dependence, and reduced ...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 38

    Assessing the likelihood and magnitude of a population health benefit following market introduction of a modified risk tobacco product (MRTP)

    CURTIN G.(1); SULSKY S.(2); BACHAND A.(2)
    (1) RAI Services Co., Winston-Salem, NC, U.S.A.; (2) Ramboll Environ US Corp., Amherst, MA, U.S.A.
    The evaluation and implementation of tobacco policies intended to reduce harm to the population as a whole, including tobacco users and non-users, must assess the potential for both intended and unintended consequences associated with those policies. ...