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12 results

  1. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 057

    AKR1C1 as a biomarker for differentiating the biological effects of combustible from non-combustible tobacco products

    TRAN Q.T.(1); WOO S.(2); HENDERSON D.(2); GAO H.(3); ZACHARIAS W.(3); LIU G.(1); PRASAD G.L.(1)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Axio Research, Seattle, WA, USA; (3) University of Louisville School of Medicine, Louisville, KY, USA
    Smoking has been established as a major risk factor for developing oral squamous cell carcinoma (OSCC), but less attention has been paid to the effects of smokeless tobacco products. Our objective is to identify potential biomarkers to distinguish...
  2. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 06

    Combusted, but not smokeless tobacco product preparations, cause DNA damage in human oral cavity cells

    ZACHARIAS W.(1); GAO H.(1); PRASAD G.L.(2)
    (1) Dept. of Medicine, J.G. Brown Cancer Center, University of Louisville, Louisville, KY, USA; (2) R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA
    We examined the effects of reference tobacco preparations on DNA damage in human oral cavity cells. The oral squamous cell carcinoma cell line (101A), normal human gingival epithelial cells (HGEC), and human gingival fibroblasts (HGF) were treated...
  3. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 30

    Combusted, but not smokeless tobacco product preparations, cause DNA damage in human oral cavity cells

    ZACHARIAS W.(1); HONG GAO(1); PRASAD G.L.(2)
    (1) Brown Cancer Center, Univ. of Louisville, Louisville, KY, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    We examined the effects of reference tobacco preparations on DNA damage in human oral cavity cells. The oral squamous cell carcinoma cell line (101A), normal human gingival epithelial cells (HGEC), and human gingival fibroblasts (HGF) were treated...
  4. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 30

    Microarray-based gene expression profiles of oral cavity cells exposed to different tobacco preparations.

    ZACHARIAS W.(1); HONG G.(1); PRASAD G.L.(2)
    (1) Dept. of Medicine, J.G. BROWN Cancer Center, Univ. of Louisville, Louisville, KY; (2) RJ Reynolds Tobacco Co., Winston-Salem, NC, USA
    Global gene expression profiles were determined for a panel of oral cavity cells in response to treatment by different tobacco preparations. Two human oral squamous cell carcinoma cell lines (101A, 101B) and normal gingival epithelial cells (HGEC)...
  5. Bull. Spec. CORESTA Congress, Lisbon, 2000, p. 107, APOST6 (adjourned)

    Estimation of the state of nitrogen nourishment of tobacco using the N-tester

    KOWALCZYK-JUSKO A.; KOSCIK B.
    University of Agriculture, Lublin - Institute of Agricultural Sciences, Zamosc, Poland.
    The purpose of this work, based on a three years of field experiment, was to inspect whether it is possible to use a chlorophyll meter in fixing the nitrogen doses used in growing flue-cured tobacco. The relationship between the capacity of nitrogen...
  6. Bull. Spec. CORESTA Congress, Brighton, 1998, p. 112, APOST13

    Influence of aqua terra hydrogel on growth, development and yield of light cigarette tobacco

    KOSCIK B.; KOWALCZYK-JUSKO A.
    University of Agriculture, Lublin - Institute of Agricultural Sciences, Zamosc, Poland.
    The aim of introductory field and pot experiments which were carried out in Zamosc in the years of 1995-1997 was to study the influence of Aqua Terra hydrogel on the growth, development and yield of light cigarette tobacco. Hydrogels are substances...