Search Results

70 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 20

    Implications of chloride application rate and nitrogen fertilizer source on flue-cured tobacco

    VANN M.C.(1); HARDY D.H.(2); FISHER L.R.(1)
    (1) North Carolina State University, Department of Crop & Soil Sciences, Raleigh, NC, U.S.A.; (2) North Carolina Department of Agriculture & Consumer Services - Agronomic Division, Raleigh, NC, U.S.A.
    Chloride (Cl-) assimilation by flue-cured tobacco can be toxic and may negatively impact leaf quality and combustion when tissue concentration exceeds 1 %. Uptake is influenced by exposure to NH4+ and Cl-, particularly that coming from fertilizer....
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 44

    Lung biomarkers of harm/effect for tobacco regulatory research: opportunities and challenges – a literature review

    MAKENA P.(1); EDMISTON J.(2); BEATTIE E.(3); MASON E.(4); McEWAN M.(5); PRASAD K.(5)
    (1) RAI Services Company, Winston-Salem, NC, U.S.A.; (2) Altria Client Services LLC, Richmond, VA, U.S.A.; (3) Cliantha Research Limited, Canada; (4) Imperial Brands PLC, Bristol, U.K.; (5) British American Tobacco (Investments) Limited, Southampton, U.K.
    Biomarkers of potential harm (BoPH) are indicators of biological perturbations in response to smoking, which may contribute to smoking-related disease. In this review, a project of the CORESTA Biomarkers Sub-Group, we critically assessed the...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST Sustainability Forum

    Smoke-Techno Sustainability Forum

    RUSSELL C.(1); THOMPSON J.(2); RAVERDY-LAMBERT D.(3); MÜHLBACHER I.(4); COLARD S.(5)
    (1) Centre for Substance Use Research (CSUR), Glasgow, Scotland, U.K.; (2) Imperial Brands PLC, Bristol, U.K.; (3) SWM International, Le Mans, France; (4) Ökolab, Vienna, Austria; (5) CORESTA, Paris, France
    In 2015, the United Nations published 17 sustainable development goals and their corresponding targets to be achieved by 2030. Like other sectors, the tobacco and alternative product sectors are likely to impact most of the...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 33

    Quantitative risk assessment (QRA) indicates reduced risk potential for carcinogenic and non-carcinogenic effects of the aerosol of the next generation products (NGPs) compared to reference cigarettes

    AYALA-FIERRO F.(1); CZEKALA L.(2); SIMMS L.(2); RUDD K.(2); CAVA G.(2); STEVENSON M.(2)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) Imperial Brands PLC, Bristol, U.K.
    In order to understand the potential relative health risks of NGPs compared to cigarettes, we compared the relative risks of aerosols from tobacco-containing and tobacco-free NGPs to the smoke generated from a reference cigarette. Quantitative Risk...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 34

    Next generation product aerosols induce lower biological activity than combusted cigarettes: a comparison of in vitro cell migration in the scratch wound assay

    RUDD K.(1); BUDDE J.(2); TRELLES STICKEN E.(2); WIECZOREK R.(2); SIMMS L.(1); STEVENSON M.(1)
    (1) Imperial Brands PLC, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    Smoking combustible cigarettes is a cause of serious diseases in smokers, including heart disease. There are many commercially available next generation products (NGPs), such as tobacco-free e-vapour products, aiming to provide an alternative to...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 49

    The CORESTA in vitro test battery for combustible tobacco products: update from the 2004 Rationale and Strategy Report

    LEE K.M.(1); JORDAN K.G.(2); WIECZOREK R.(3); MOENNIKES O.(4); CLEMENTS J.(5); CROOKS I.(6); HASHIZUME T.(7); MILLER J.(8); WEBER E.(9); YOSHINO K.(7)
    (1) Altria Client Services, Richmond, VA, U.S.A.; (2) RAI Services Company, Winston-Salem, NC, U.S.A.; (3) Imperial Brands, Reemtsma Cigarettenfabriken GmbH, Hamburg, Germany; (4) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (5) Covance Laboratories Ltd, Harrogate, U.K.; (6) British American Tobacco (Investments) Ltd, R&D, Southampton, U.K.; (7) Japan Tobacco Inc., Yokohama, Kanagawa, Japan; (8) JT International SA, Geneva, Switzerland; (9) Ökolab, Vienna, Austria
    In 2004, the CORESTA In Vitro Toxicity Task Force issued a rationale and strategy report, commonly known as “the CORESTA in vitro test battery guideline”. The goals of this guideline were to: 1) develop the rationale and strategy for conducting in...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STW 01

    The application of in vitro Toxicity Testing in 21 Century (TT21C) for next generation products

    SIMMS L.(1); TRELLES STICKEN E.(2)
    (1) Imperial Brands PLC, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    The aim is to demonstrate the feasibility of TT21C in vitro methods as part of an overall assessment framework for next generation products (NGP). TT21C methodologies can be used to assess harm reduction potential of NGPs using human-derived...
  8. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 021

    Influence of the time of and stirring rate during the first step of synthesis of SBA-15 on its catalytic effect for reducing toxicants concentration in tobacco smoke

    JUÁREZ-SERRANO N.; ASENSIO-MORANT J.; MARTÍNEZ-CASTELLANOS I.; BERENGUER D.; BLASCO I.; BELTRÁN M.I.; MARCILLA A.
    University of Alicante, Alicante, Spain
    Certain mesoporous materials can modify notably the composition of smoke tobacco, since they can act as catalysts and/or adsorbents allowing to reduce the toxic and carcinogenic compounds of the smoke. However, the properties of the catalysts...
  9. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 023

    Effect of SBA-15 morphology in the composition of the mainstream tobacco smoke

    MARTÍNEZ-CASTELLANOS I.; MARCILLA A.; BELTRÁN M.I.; BERENGUER D.; BLASCO I.; JUAREZ N.; ASENSIO J.; CALABUIG E.
    University of Alicante, Alicante, Spain
    Mesoporous silica materials, such as SBA-15, are attracting increasing interest in the last years. Our research group has focused in their capability for reducing the toxic compounds generated in the smoking process when mixed with tobacco. By tuning...