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43 results

  1. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 049

    High throughput air liquid interface exposure modules: characterization of smoke/aerosol dosimetry and in vitro mutagenicity and cytotoxicity of two tobacco product types

    LEVERETTE R.(1); KEYSER B.(1); HOLLINGS M.(2); SEYMOUR A.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Covance Laboratories, North Yorkshire, UK
    The utilization of whole smoke/aerosol exposure systems provides a means to conduct in vitro assessments of freshly generated whole smoke/aerosol from combustible cigarettes and tobacco heating products (THPs), as well as electronic nicotine delivery ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 25

    A clinical study in Japanese smokers investigating changes in exposure to cigarette smoke chemicals in participants who switch to using a tobacco heating product for a five day period

    GALE N.(1); McEWAN M.(1); ELDRIDGE A.(1); ERRINGTON G.(1); McDERMOTT S.(2); GLEW J.(2); HEDGE A.(2); MURPHY J.(1); PROCTOR C.J.(1); FEARON I.(1)
    (1) British American Tobacco (Investments) Limited, R&D, Southampton, U.K.; (2) Covance Inc., Leeds, U.K.
    Tobacco heating products (THP) are electronic devices that heat tobacco, rather than combusting it. Due to this lack of combustion, significantly fewer toxicants are formed but nicotine is still released into the inhaled aerosol. Clinical studies ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 64

    A novel approach for the screening of e-cigarette aerosols using an Ames whole aerosol assay

    THORNE D.(1); HOLLINGS M.(2); SEYMOUR A.(2); CROOKS I.(1); MEREDITH C.(1); GAҪA M.(1)
    (1) British American Tobacco (Investments) Limited, R&D, Southampton, U.K.; (2) Covance Laboratories Ltd, Harrogate, North Yorkshire, U.K.
    The in vitro mutagenic potential of the aerosol from Vype ® ePen e-cigarette was assessed using the Ames assay. E-cigarette aerosol was trapped on a Cambridge filter pad, eluted in DMSO and compared to cigarette smoke total particulate matter (TPM), ...
  4. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 106

    A study to examine changes in exposure to cigarette smoke chemicals when a smoker switches to using a tobacco heating product. Part I: study design

    GALE N.(1); McEWAN M.(1); ELDRIDGE A.(1); CAMACHO O.M.(1); McAUGHEY J.(1); MURPHY J.(1); LIU C.(1); PROCTOR C.J.(1); FEARON I.M.(1); SHERWOOD N.(2); BOWEN E.(3); McDERMOTT S.(3); HOLMES E.(3)
    (1) British American Tobacco (Investments) Ltd, Southampton, UK; (2) Neil Sherwood Consulting, Commugny, Switzerland; (3) Covance, Leeds, UK
    A tobacco heating product (THP), glo™, which heats rather than combusts tobacco and produces significantly reduced machine yields of chemical toxicants compared to combustible cigarettes, was assessed in this study. Biomarker of exposure (BoE) studies are ...
  5. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 107

    A study to examine changes in exposure to cigarette smoke chemicals when a smoker switches to using a tobacco heating product. Part II: study findings

    GALE N.(1); ELDRIDGE A.(1); McEWAN M.(1); ERRINGTON G.(1); MURPHY J.(1); PROCTOR C.J.(1); FEARON I.M.(1); McDERMOTT S.(2); GLEW J.(2); HEDGE A.(2)
    (1) British American Tobacco (Investments) Ltd, Southampton, UK; (2) Covance, Leeds, U.K.
    A tobacco heating product (THP), glo™, which heats rather than combusts tobacco and produces significantly reduced machine yields of chemical toxicants compared to combustible cigarettes, was assessed in this study. Biomarker of exposure (BoE) studies are ...
  6. CORESTA Meeting, Agronomy/Phytopathology, 2015, Izmir, Turkey, AP 35

    Measuring canopy nitrogen nutrition in tobacco plants using hyper spectrum parameters

    ZOU Yong; YE Xiaoqing; YU Zhihong; CHEN Yufeng; WANG Wei; CHEN Jianjun
    (1) Shenzhen Tobacco Ind. Co., Ltd. of CNTC, Shenzhen, Guangdong, P.R. China; (2) Shenzhen Boton Flavors & Fragrances Co., Ltd., Shenzhen, Guangdong, P.R. China; (3) Tobacco Laboratory, South China Agricultural University, Guangzhou, Guangdong, P.R. China
    The aim of this paper is to study the quantitative relationship between above-ground nitrogen accumulation (ANA) of flue-cured tobacco and canopy spectral parameters, and then build a monitoring model for ANA of flue-cured tobacco based on various ...
  7. CORESTA Meeting, Smoke Science/Product Technology, Jeju, 2007, SSPT 13

    Fast on-line tobacco smoke analysis with Photo Ionisation - Time-of-Flight-Mass Spectrometry - Part 1: Scientific background and basic principles

    ZIMMERMANN R.; MÜHLBERGER F.; MITSCHKE S.; STREIBEL T.; ROSE N.
    University of Augsburg, Analytical Chemistry, Institute of Physics, Augsburg, Germany
    Mass spectrometry (MS) with soft ionisation (i.e. non fragmenting ionisation) allows a direct on-line monitoring of organic compounds in complex gaseous matrices such as tobacco smoke. Photo ionisation (PI) methods are particularly well suited for this ...
  8. CORESTA Meeting, Smoke Science/Product Technology, Jeju, 2007, SSPT 15

    Fast on-line tobacco smoke analysis with Photo Ionisation - Time-of-Flight-Mass Spectrometry - Part 3: First measurements with a Smoke Analyzer Prototype system

    MITSCHKE S.; ROSE N.; ZIMMERMANN R.
    University of Augsburg, Analytical Chemistry, Institute of Physics, Augsburg, Germany
    In the past few years several studies were undertaken investigating mainstream and sidestream smoke with modern on-line mass spectrometric methods with soft ionisation methods, such as single-photon ionisation (SPI) and resonant multi photon ionisation ...
  9. CORESTA Meeting, Smoke Science/Product Technology, Jeju, 2007, SSPT 19

    Simultaneous on-line analysis of gas phase and particulate phase of cigarette mainstream smoke

    ADAM T.; McAUGHEY J.; MITSCHKE S.; McGRATH C.; MOCKER C.; ZIMMERMANN R.
    University of Augsburg, Analytical Chemistry, Institute of Physics, Augsburg, Germany
    Tobacco smoke is a complex and dynamic matrix consisting of gaseous and particulate material, in which about 4800 constituents have been identified. The chemical composition and partition between phases of the smoke can change continuously and is strongly ...
  10. CORESTA Meeting, Smoke Science/Product Technology, Jeju, 2007, SSPT 20

    Sidestream smoke analysis with Single Photon Ionisation/Time-of-Flight Mass Spectrometry (SPI-TOFMS)

    MITSCHKE S.; ADAM T.; BAKER R.R.; ZIMMERMANN R.
    University of Augsburg, Analytical Chemistry, Institute of Physics, Augsburg, Germany
    Recently several studies dealing with online analysis of mainstream tobacco smoke utilising photo ionisation mass spectrometry (PI-MS), namely single photon ionisation (SPI) and resonance-enhanced multi photon ionisation (REMPI) time-of-flight mass ...