Search Results

42 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 19

    In vitro biological impact evaluation of whole cigarette smoke by using pathway-based approach

    CHEN H.(1,2); CHEN X.(1,2); SHEN Y.(3); LIU F.(1,2); YIN X.(1); LIU L.(1); TIMKO M.(4); QI H.(5); FAN L.(1,2,3)
    (1) Institute of Crop Science, Zhejiang University, Hangzhou, P.R. China; (2) Research Center for Air Pollution and Health, Zhejiang University, Hangzhou, P.R. China; (3) Institute of Bioinformatics, Zhejiang University, Hangzhou, P.R. China; (4) Department of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, VA, U.S.A.; (5) Department of Pathology and Pathophysiology, School of Basic Medical Sciences, Zhejiang University, Hangzhou, P.R. China
    Harm-reduced cigarettes have been greatly developed to minimize the negative impact of smoking on health. However, the practical effects of such products are still under debate. Along with the application of high-throughput sequencing technologies (such ...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 01

    In vitro biological safety evaluation of cigarette smoke

    CHEN Xi(1,2); SHEN Y.(1,2); CHEN Hongyu(1,2); LIU F.(1,2); QI H.(3); JIMIN S.(3); TIMKO M.(4); FAN L.(1,2)
    (1) Research Center for Air Pollution and Health, Zhejiang University, Hangzhou, P.R. China; (2) Institute of Bioinformatics, Zhejiang University, Hangzhou, P.R. China; (3) Department of Pathology and Pathophysiology, School of Basic Medical Sciences, Zhejiang University, Hangzhou, P.R. China; (4) Department of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, VA, U.S.A.
    Traditionally, toxicological evaluation of cigarette smoke has focused on the harmful chemical content of smoke. Harm-reduced cigarettes should not only refer to these chemical compounds, but also to the degree of the effect of whole smoke on human cells. ...
  3. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 44

    Investigation of pyrolysis behaviour of lutein in air by thermo gravimetry-single drop micro extraction-gas chromatography-mass spectrometry

    YANG Ji; YANG Liu; WU Yiqin; MIAO Mingming; ZHE Wei; CHEN Yongkuan
    China Tobacco Yunnan Industrial Co., Ltd of CNTC, R&D Center, Kunming, P.R. China
    To investigate the pyrolysis behaviour of lutein in air, an automatic single drop micro extraction (SDME) device for trapping the released fractions was designed and coupled with thermo gravimetry-gas chromatography-mass spectrometry. According to the ...
  4. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 57

    Alterations in human bronchial epithelial cell transcriptomes following exposure to mainstream smoke from tobacco and non-tobacco cigarettes

    TIMKO M.P.; WOLKOWICZ M.J.; KOTOVA T.
    University of Virginia, Charlottesville, VA, USA
    Increased public awareness of the health risks associated with smoking has led to the development of numerous products aimed at promoting smoking cessation by purportedly reducing nicotine addiction and the harmful effects of tobacco smoke exposure. Using ...
  5. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 58

    RNA-seq analysis of alterations in human bronchial epithelial cell transcriptomes following exposure to electronic (e)-cigarette vapors

    TIMKO M.P.; WOLKOWICZ M.J.; KOTOVA T.; HOLBY S.N.
    University of Virginia, Charlottesville, VA, USA
    Increased public awareness and governmental concern of the health risks associated with smoking has led to the development of products aimed at reducing the harmful effects of tobacco smoke exposure and potentially promoting smoking cessation. Electronic ...
  6. Tobacco Science & Technology, 2011, 7, p. 60-63., ISSN.1002-0861

    Transfer behavior of some carbonyl flavors in filter and tobacco rod of cigarette

    ZHANG JIE(1); ZONG YONG-LI(1); ZHOU HUI-SHUN(2); PENG SHU-HAI(1); SONG YU-BING(1)
    1. Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, P.R. China; 2. Technology Center of China Tobacco Jiangxi Industrial Corporation, Nanchang 330096, P.R. China
    Twelve carbonyl flavor samples were added into cut tobacco and filter tips of cigarettes and then analyzed by simultaneous distillation and extraction coupled with GC and GC/MS to determine the ratios of flavor retained in tobacco rod or filter, migrated ...
  7. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 02

    Functional genomics approaches to harm reduction in tobacco products

    TIMKO M.P.; RUSHTON P.J.; BOKOWIEC M.T.; ZHANG Hongbo
    University of Virginia, Dept. of Biology, Charlottesville, VA, USA; South Dakota State University, Dept. of Biology and Microbiology, Brookings, SD, USA
    There is overwhelming evidence that the use of tobacco products plays a major role in the pathogenesis of lung and oral cancers, cardiovascular disease, COPD, and a variety of other human diseases. In the absence of complete elimination of their use, a ...
  8. Tobacco Science & Technology, 2010, 8, p. 41-45., ISSN.1002-0861

    Effects of filter length and ventilation on transfer behavior of some ester flavors in cigarette

    ZHOU HUI-SHUN(1); ZONG YONG-LI(2); ZHANG JIE(2); PENG SHU-HAI(2); SONG YU-BING(2)
    1. Technology Center, P.R. China Tobacco Jiangxi Industrial Corporation, Nanchang 330096, P.R. China; 2. Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, P.R. China
    In order to investigate the effects of filter length and ventilation on the transfer behavior of some ester flavors in cigarettes, the said ester flavors were injected into cigarettes with filters of various length and ventilation rates. These flavored ...