Search Results

89 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, APPOST 10

    The influence of sodium carbonate buffer on TSNAs accumulation and leaf quality during tobacco storage

    LIU Xingyu(1); LIU Deshui(1); MA Li(1); MA Yanjun(1); YANG Zhendong(1); ZHANG Jie(1); LIN Lin(2); BAI Ruoshi(1); ZHOU Jun(1)
    (1) Technology Center, Shanghai Tobacco Group Co., Ltd., Beijing, P.R. China; (2) Beijing Tobacco Quality Supervision and Testing Station, Beijing, P.R. China
    Storage of tobacco leaves is an important stage in tobacco processing. Tobacco Specific N-nitrosamines (TSNAs) in tobacco leaves gradually increase during storage. The purpose of this study was to investigate the influence of sodium carbonate on the ...
  2. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 041

    Analysis of e-liquids of electronic cigarettes containing nicotine salts

    HAN Shulei; Fu Yaning; Liu Tong; Wang Hongjuan; Chen Huan; Hou Hongwei
    China National Tobacco Quality Supervision and Test Center, Henan, P.R. China
    Electronic cigarettes containing nicotine salts are gaining in more and more popularity worldwide. However, information about this kind of products is very limited. We developed a high performance liquid chromatography method for simultaneously ...
  3. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 050

    Cytotoxicity and acute toxicity assessment of several typical nicotine salts

    WANG Hongjuan; CHEN Huan; HAN Shulei; FU Yaning; LIU Tong; HOU Hongwei; HU Qingyuan
    China National Tobacco Quality Supervision & Test Center, Henan, P.R. China
    As a new form of nicotine intake, nicotine salts are increasingly used in new tobacco products such as electronic cigarette. Whether the matrix components of electronic liquids will affect its toxicity, relative to pure nicotine, how to set the ...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 59

    An inter-laboratory comparison study focused on the determination of total NNAL in human urine

    NEWLAND K.(1); SCHERER M.(2); HECHT S.S.(3); TROUDE V.(4); PRASAD G.L.(5)
    (1) Celerion Inc., Lincoln, NE, U.S.A.; (2) ABF GmbH, Planegg, Germany; (3) University of Minnesota Cancer Center, Minneapolis, MN, U.S.A.; (4) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (5) RAI Services Company, Winston-Salem, NC, U.S.A.
    In an ongoing effort to fulfil the second objective of the CORESTA Biomarker Sub-Group, periodic inter-laboratory comparison studies have been performed to evaluate the consistency of the quantitation for various harmful or potentially harmful exposure ...
  5. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 52

    Biological test procedure for fresh generated cigarette smoke and e-cigarette aerosols under air-liquid interface (ALI) exposure in 24 and 96 multi-well plates

    WIECZOREK R.(1); TRELLES STICKEN E.(1); WALELE T.(2); CZEKALA L.(3); SIMMS L.(3)
    (1) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (2) Fontem Ventures, Amsterdam, The Netherlands; (3) Imperial Tobacco Limited, Bristol, U.K.
    Cigarette smoke and e cigarette aerosol contain particulate matter/liquid droplets in the solid phase as well as volatile substances in the gas phase. Both fractions are of potential toxicological relevance and should be considered when assessing ...
  6. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 53

    Use of human derived cell lines to increase the biological relevance of cigarette condensate, non-tobacco materials and e-liquids testing

    WIECZOREK R.(1); TRELLES STICKEN E.(1); WALELE T.(2); CZEKALA L.(3); SIMMS L.(3)
    (1) Reemtsma Cigarettenfabriken GmbH, Imperial Brands plc, Hamburg, Germany; (2) Fontem Ventures, Amsterdam, The Netherlands; (3) Imperial Tobacco Limited, Bristol, U.K.
    The in vitro testing strategy of tobacco products is mainly based on the testing of extracts from cigarette smoke condensates. An accepted industry wide assay battery has been developed over recent years which delivers reliable results for the ...
  7. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 049

    Assessment of in vitro toxicity/genotoxicity of ends and combustible products

    JORDAN K.(1); BOMBICK B.(1); COOPER B.(1); LEVERETTE R.(1); SHUTSKY T.(1); WEST C.(1); STRASSER J.(1); ROUND E.(1); MARANO K.M.(1); MOMIN R.(2); TRIVEDI A.(2); WAGSTAFF W.(2); BRUCE S.(3); DAKOULAS E.(3); ROY S.(3)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Labstat International ULC, Kitchener, ON, Canada; (3) BioReliance Corp, Rockville, MD, USA
    In May 2016, the U.S. Food and Drug Administration Center for Tobacco Products (CTP) issued draft guidance for Premarket Tobacco Product Applications (PMTA) for Electronic Nicotine Delivery Systems (ENDS), which recommends inclusion of in vitro toxicology ...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 22

    Estimation of e-cigarette aerosol yields based on puff duration

    JULIEN R.(1); TSCHIERSKE N.(2); VARIGNON B.(1); TROUDE V.(1); DESTRUHAUT S.(1); WALELE T.(3); COLARD S.(1); CAHOURS X.(1)
    (1) SEITA-Imperial Tobacco Limited, Fleury-les-Aubrais, France; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (3) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands
    There are regulatory requirements in quantifying and comparing the emission levels of major and minor aerosol constituents from e-cigarettes. Up until the recent publication in 2015 of CORESTA Recommended Method (CRM) No. 81- " Routine Analytical ...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 07

    Consistency of bluTM e-cigarette nicotine delivery according to the AFNOR standard

    TSCHIERSKE N.(1); JULIEN R.(2); VARIGNON B.(2); TROUDE V.(2); DESTRUHAUT S.(2); WALELE T.(3); COLARD S.(2); CAHOURS X.(2)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (2) SEITA-Imperial Tobacco Limited, Fleury-les-Aubrais, France; (3) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands
    Demonstrating the consistency of nicotine delivery from an e-cigarette is a requirement per EU Tobacco Product Directive (TPD) 2, Article 20, 3(f) (The European Council and the Council of the European Union, 2014). The Directive states that e-cigarettes ...
  10. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 08

    Indoor air quality and surface deposition assessment following use of an open system e-cigarette

    BAUER N.(1); TSCHIERSKE N.(1); O'CONNELL G.(2); CAHOURS X.(3)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (2) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands; (3) SEITA-Imperial Tobacco Limited, Fleury-les-Aubrais, France
    Electronic cigarette (e-cigarette) nicotine delivery devices are growing in popularity worldwide. Both regulators and public health organisations are beginning to examine potential implications that exposure to exhaled e-cigarette aerosol may have on non ...