Search Results

67 results

  1. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 24

    Influences of chronic alcohol consumption and critical enzyme regulation on the in vivo metabolism of NNK in mice

    MAO Jian(1); ZHANG Qidong(1); WANG Ronghao(1); LI Chen(1); LIU Shuaidong(2); CHAI Guobi(1); WANG Dingzhong(1); XI Hui(1); LIU Junhui(1); ZHANG Jianxun(1)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China; (2) Technology Center of China Tobacco Shaanxi Industrial Co., Ltd., Baoji, Shaanxi, P.R. China
    The progressive clarification of influential factors on the in vivo metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), one of the potent carcinogens in tobacco, could provide valuable information for precisely evaluating the health risk ...
  2. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 51

    Investigate particle size distributions of electronic cigarette aerosols using a multi-angle light scattering instrument

    SONG C.(1); HOLVE D.(2); ALDERMAN S.L.(1)
    (1) R.J. Reynolds Tobacco Company, Winston Salem, NC USA; (2) EnviroMetrix Instruments LLC, Berkeley, CA USA
    Particle size distribution measurement of electronic cigarette aerosols represents a great experimental challenge due to the volatile nature of the particulate compositions and the high number density (up to 1010 per cubic centimeter). Efforts have been ...
  3. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, STPOST 17

    Global profiling of metabolites from saliva of tobacco consumers

    PRASAD G.L.(1); JONES B.A.(1); SCHMIDT E.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Company, R&D Department, Winston-Salem, NC, U.S.A.; (2) Metabolon, Durham, NC, U.S.A.
    The long-term health effects associated with cigarette smoking have been shown to be more harmful compared to those associated with the consumption of non-combustible tobacco products, such as moist snuff. In order to investigate the long-term health ...
  4. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 17

    Global profiling of metabolites from saliva of tobacco consumers

    PRASAD G.L.(1); JONES B.A.(1); SCHMIDT E.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA; (2) Metabolon, Durham, North Carolina, USA
    The long-term health effects associated with cigarette smoking have been shown to be more harmful compared to those associated with the consumption of non-combustible tobacco products, such as moist snuff. In order to investigate the long-term health ...
  5. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 38

    Analysis of free amino acids in tobacco with a new LC/MS/MS procedure

    MOLDOVENAU S.C.(1); ZHU J.(2)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA; (2) Lancaster Labs. Inc., Winston-Salem, North Carolina, USA
    The levels of amino acids in tobacco are important for leaf characterization. They contribute substantially to the level of toxicants in cigarette smoke, and to the sensory properties of cigarettes. The analysis of amino acids in tobacco leaf has been ...
  6. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPT 24

    Development of biomarkers of effect from chronic tobacco usage. Part 3: Potential metabolomics biomarkers of tobacco effect

    PRASAD G.L.(1); CHEN P.(1); JONES B.A.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA; (2) Metabolon, Durham, NC, USA
    Epidemiological data indicate that consumption of moist snuff is associated with reduced harm relative to cigarette smoking. However, a need exists for interim biomarkers of effect (BioEff) that would be useful to assess the health effects of tobacco. To ...
  7. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 36

    Development of biomarkers of effect from chronic tobacco usage.Part 4: Metabolomic profiles from cigarette smokers and moist snuff consumers

    PRASAD G.L.(1); CHEN P.(1); JONES B.A.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA; (2) Metabolon, Durham, NC, USA
    The long-term health effects associated with cigarette smoking have been shown to be more harmful compared to those associated with the consumption of non-combustible tobacco products, such as moist snuff. In order to investigate the long-term effects of ...
  8. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 23

    Development of biomarkers of effect from chronic tobacco usage: Part 4. Metabolomic profiles from cigarette smokers and moist snuff consumers

    PRASAD G.L.(1); CHEN P.(1); JONES B.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA; (2) Metabolon, Inc., Durham, NC, USA
    The long-term health effects associated with cigarette smoking have been shown to be more harmful compared to those associated with the consumption of non-combustible tobacco products, such as moist snuff. In order to investigate the long-term effects of ...
  9. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 26

    Development of biomarkers of effect from chronic tobacco usage: Part 3. Potential metabolomics biomarkers of tobacco effect.

    PRASAD G. L.(1); CHEN P.(1); JONES B.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA; (2) Metabolon, Inc., Durham, NC, USA
    Epidemiological data indicate that consumption of moist snuff is associated with reduced harm relative to cigarette smoking. However, a need exists for interim biomarkers of effect (BioEff) that would be useful to assess the health effects of tobacco. To ...
  10. Tobacco Science & Technology, 2012, 10, p. 13-15, ISSN.1002-0861

    Stabilizing technical parameters in cut tobacco drying with moisture content parallel shift method

    ZHAO Hanwen(1); ZHANG Jun(2); LI Na(2)
    (1) Technology Center, China Tobacco Shaanxi Industrial Co., Ltd., Baoji 721013, Shaanxi, P.R. China; (2) Baoji Cigarette Factory, China Tobacco Shaanxi Industrial Co., Ltd., Baoji 721013, Shaanxi, P.R. China
    In order to stabilize the technical parameters in cut tobacco drying, the moisture content in cut tobacco before and after drying was simultaneously adjusted with moisture content parallel shift method. The variation of running parameters of cut tobacco ...