Search Results

67 results

  1. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, APPOST 30

    Nicotine reduction and consumer perception: a scientific approach for quantifying possible impact of low nicotine cigarettes on consumer behaviour

    GUO Mengran(1); VERRON T.(1); DORLHAC de BORNE F.(2); PRITCHARD J.(3); COLARD S.(1)
    (1) SEITA - Imperial Brands plc, Paris, France; (2) Imperial Tobacco Limited, Leaf Research, Bergerac, France; (3) Imperial Brands, Bristol, U.K.
    In 2015, the WHO Study Group on Tobacco Product Regulation (TobReg) issued an advisory note recommending a strategy to reduce nicotine in tobacco to levels which would not be sufficient to lead to the development and/or maintenance of addiction. In the US ...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 60

    Assessing changes in biomarkers of effect in smokers who switch to a closed system electronic cigarette

    MASON L.; CAHOURS X.; O'CONNELL G.; WALELE T.
    Imperial Brands, Bristol, U.K.
    Previous studies have demonstrated that when smokers switch to an electronic cigarette, they are exposed to significantly lower levels of carcinogens and toxicants. As a result, there is a reported significant reduction in biomarkers of exposure to levels ...
  3. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 39

    The use of high content screening (HCS) in human primary lung cells to assess e-liquids of differing flavors and nicotine concentrations

    SIMMS L.(1); CZEKALA L.(1); STEVENSON M.(1); PHILLIPS G.(1); WALELE T.(2)
    (1) Imperial Brands, Bristol, U.K.; (2) Fontem Ventures, Amsterdam, The Netherlands
    Due to the current scientific debate and evolving regulatory landscape, new assays are needed to quickly determine the subtle biological response of e-liquids for both stewardship and product development purposes. For stewardship, all ingredients in the e ...
  4. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 51

    Investigate particle size distributions of electronic cigarette aerosols using a multi-angle light scattering instrument

    SONG C.(1); HOLVE D.(2); ALDERMAN S.L.(1)
    (1) R.J. Reynolds Tobacco Company, Winston Salem, NC USA; (2) EnviroMetrix Instruments LLC, Berkeley, CA USA
    Particle size distribution measurement of electronic cigarette aerosols represents a great experimental challenge due to the volatile nature of the particulate compositions and the high number density (up to 1010 per cubic centimeter). Efforts have been ...
  5. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, STPOST 17

    Global profiling of metabolites from saliva of tobacco consumers

    PRASAD G.L.(1); JONES B.A.(1); SCHMIDT E.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Company, R&D Department, Winston-Salem, NC, U.S.A.; (2) Metabolon, Durham, NC, U.S.A.
    The long-term health effects associated with cigarette smoking have been shown to be more harmful compared to those associated with the consumption of non-combustible tobacco products, such as moist snuff. In order to investigate the long-term health ...
  6. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 17

    Global profiling of metabolites from saliva of tobacco consumers

    PRASAD G.L.(1); JONES B.A.(1); SCHMIDT E.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA; (2) Metabolon, Durham, North Carolina, USA
    The long-term health effects associated with cigarette smoking have been shown to be more harmful compared to those associated with the consumption of non-combustible tobacco products, such as moist snuff. In order to investigate the long-term health ...
  7. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 38

    Analysis of free amino acids in tobacco with a new LC/MS/MS procedure

    MOLDOVENAU S.C.(1); ZHU J.(2)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA; (2) Lancaster Labs. Inc., Winston-Salem, North Carolina, USA
    The levels of amino acids in tobacco are important for leaf characterization. They contribute substantially to the level of toxicants in cigarette smoke, and to the sensory properties of cigarettes. The analysis of amino acids in tobacco leaf has been ...
  8. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPT 24

    Development of biomarkers of effect from chronic tobacco usage. Part 3: Potential metabolomics biomarkers of tobacco effect

    PRASAD G.L.(1); CHEN P.(1); JONES B.A.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA; (2) Metabolon, Durham, NC, USA
    Epidemiological data indicate that consumption of moist snuff is associated with reduced harm relative to cigarette smoking. However, a need exists for interim biomarkers of effect (BioEff) that would be useful to assess the health effects of tobacco. To ...
  9. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 36

    Development of biomarkers of effect from chronic tobacco usage.Part 4: Metabolomic profiles from cigarette smokers and moist snuff consumers

    PRASAD G.L.(1); CHEN P.(1); JONES B.A.(1); KENNEDY A.D.(2)
    (1) R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA; (2) Metabolon, Durham, NC, USA
    The long-term health effects associated with cigarette smoking have been shown to be more harmful compared to those associated with the consumption of non-combustible tobacco products, such as moist snuff. In order to investigate the long-term effects of ...