CORESTA Congress, Shanghai, 2008, AP 05
Down-regulating the nicotine demethylase gene lowers NNN content levels with little or no effect on field performance of Burley and dark tobaccos
U.S. Smokeless Tobacco Co., Winchester, KY, USA
Down-regulating nicotine demethylase (ND) activity in tobacco using RNAi interference mechanisms or by mutating the ND gene reduces nornicotine formation and should lead to lowering N-nitroso-nornicotine (NNN) levels in cured leaf. Over the past two years ...