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153 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 27

    Next generation product aerosol bubbled extracts show little to no effect in high content screening endpoints when compared to cigarette smoke bubbled extracts

    TRELLES STICKEN E.(1); WIECZOREK R.(1); BODE L.M.(1); SIMMS L.(2); STEVENSON M.(2)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), BioToxLab, Hamburg, Germany; (2) Imperial Tobacco Limited, In vitro Research, Bristol, U.K.
    Tobacco-based and tobacco-free next generation products (NGPs) are understood to be a less harmful alternative to conventional combustible cigarettes. The objective of this study was to compare the in vitro biological response of cigarette smoke and a ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 34

    Next generation product aerosols induce lower biological activity than combusted cigarettes: a comparison of in vitro cell migration in the scratch wound assay

    RUDD K.(1); BUDDE J.(2); TRELLES STICKEN E.(2); WIECZOREK R.(2); SIMMS L.(1); STEVENSON M.(1)
    (1) Imperial Brands PLC, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    Smoking combustible cigarettes is a cause of serious diseases in smokers, including heart disease. There are many commercially available next generation products (NGPs), such as tobacco-free e-vapour products, aiming to provide an alternative to smoking ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 37

    Use of cell media nicotine concentration as a marker to predict cells surface deposited nicotine in transwells after fresh smoke/aerosol exposure

    WIECZOREK R.(1); TRELLES STICKEN E.(1); BODE L.M.(1); SIMMS l.(2)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (2) Imperial Tobacco Limited, Bristol, U.K.
    Exposure of organotypic 3D lung models at the air liquid interface (ALI) to fresh whole smoke/aerosol provides a more human relevant exposure assessment of combustible cigarettes and e-vapour products. The aim of this study is to present a method for ...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STW 01

    The application of in vitro Toxicity Testing in 21 Century (TT21C) for next generation products

    SIMMS L.(1); TRELLES STICKEN E.(2)
    (1) Imperial Brands PLC, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    The aim is to demonstrate the feasibility of TT21C in vitro methods as part of an overall assessment framework for next generation products (NGP). TT21C methodologies can be used to assess harm reduction potential of NGPs using human-derived cellular ...
  5. CORESTA Meeting, Agronomy/Phytopathology, 2017, Santa Cruz do Sul, AP 04

    Contributions to the study of gall wasp occurrence in Eucalyptus woodlots in southern Brazil

    ROESCH F.(1); FEUERBORN M.(1); KOEHLER A.(2); RAUBER M.(2); FARIAS J.(3); WELTER C.A.(3); TEIXEIRA D.S.(3)
    (1) Japan Tobacco International (JTI), Santa Cruz do Sul, RS, Brazil; (2) Universidade de Santa Cruz do Sul (UNISC), Laboratory of Entomology, Santa Cruz do Sul, RS, Brazil; (3) Universidade Federal de Santa Maria (UFSM), Centro de Pesquisas Florestais, Campus Universitário, Santa Maria, RS, Brazil
    Firewood from Eucalyptus spp. is the main source of energy for tobacco curing in South Brazil. Leptocybe invasa Fisher & Lasalle, 2004 (Hymenoptera: Eulophidae) is a gall inducing wasp species that causes damage to eucalyptus plantations and nurseries ...
  6. CORESTA Meeting, Agronomy/Phytopathology, 2017, Santa Cruz do Sul, AP 49

    Potential alternative control for Ephestia spp. using parasitoid wasps

    KÖHLER A.(1); PEZZINI C.(1); ROESCH F.(2); FEUERBORN M.(2)
    (1) Universidade de Santa Cruz do Sul (UNISC), Laboratory of Entomology, Santa Cruz do Sul, RS, Brazil; (2) Japan Tobacco International (JTI), Santa Cruz do Sul, RS, Brazil
    Different practices are already used to control lepidopteran pests in stored tobacco, mostly including chemical or physical practices, preventive or disinfesting. Biological methods, used more frequently in tobacco field sites, are not used yet in stored ...
  7. CORESTA Congress, Berlin, 2016, Agronomy/Phytopathology Groups, APPOST 26

    Crop compliance: crop protection agents testing programme within purchases

    BODE L.M.; EVANS W.; INTORP M.
    Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    In order to ensure the compliance of our products, leaf grade purchases are monitored for the presence of any residual crop protection agents (CPA). CPA residue levels are first assessed for compliance against limits set by regulatory authorities and ...
  8. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 04

    Impact of different vaping machines on metal contaminations of e-cigarette aerosols

    OTTE S.; NOWAK S.; INTORP M.
    Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    The presence of trace metals in e-liquids or aerosol of electronic cigarettes (e-cigarette) has been previously reported [1]. It has also been demonstrated that contamination with tin, aluminum, copper, iron and nickel may occur from certain parts of a ...
  9. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 21 (also presented at TSRC 2016)

    Puff-by-puff tar, nicotine and carbonyl profiles under different smoking regimens of commercial cigarettes with various carbon filter technologies

    ROBERTSON R.M.; NORFLEET K.; CANTERBURY W.B.
    Celanese, Narrows, VA, U.S.A.
    Puff-by-puff smoke analysis has shown that the CelFX ® carbon filter technology has similar nicotine and tar smoke delivery profiles but with significantly reduced carbonyls, particularly in the first 6 puffs, compared to a cellulose acetate filter. Prior ...