Search Results

115 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 12

    Review of current methodologies in evaluating abuse liability of nicotine and tobacco products in the U.S. regulatory environment

    EVANS S.(1); KONG M.C.(2); CAMPBELL L.(2); SHERWOOD N.(3); PRASAD K.(4)
    (1) Turning Point Brands, Louisville, KY, U.S.A.; (2) Altasciences Clinical Research, Laval, Canada; (3) Neil Sherwood Consulting, Nyon, Switzerland; (4) British American Tobacco, R&D, Millbrook, Southampton, U.K.
    Traditional definitions of abuse and misuse do not apply to a consumer product such as tobacco that consumers essentially use ‘as intended’. In contrast to pharmaceutical products, a guidance for abuse liability testing of nicotine and tobacco products ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 52 (also presented at TSRC 2019)

    Application of differential ion mobility spectrometry-tandem mass spectrometry for improved assay selectivity and sensitivity in the quantitation of tobacco biomarkers NNN, NNAL and 2-/3-HPMA in human urine

    PLOMLEY J.B.
    Altasciences, Laval, QC, Canada
    Differential ion mobility spectrometry (DMS) has recently emerged as an orthogonal gas-phase ion separation technique which, when interfaced between liquid chromatography (LC) and tandem mass spectrometry (MS/MS), promises improvements in both assay ...
  3. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 044

    Abuse liability of very low nicotine content cigarettes with characterization of nicotine exposure profiles in adult smokers

    LEVY-COOPERMAN N.(1); SHRAM M.J.(1); KELSH D.(2); VINCE B.(2); CARMINES E.(3)
    (1) Altreos Research Partners, Toronto, ON, Canada; (2) Altasciences/Vince and Associates, Overland Park, KS, USA; (3) Carmines Consulting, Scottsdale, AZ, USA
    Objectives: In 2017, FDA announced the intention to explore limiting nicotine in cigarettes to minimal/non-addictive levels. Research indicates that reduced nicotine content would potentially limit reinforcing effects of cigarettes. We conducted 2 studies ...
  4. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 102 (also presented at CORESTA SSPT2019)

    Novel application of differential ion mobility spectrometry-tandem mass spectrometry for improved assay selectivity and sensitivity in the quantitative determination of total NNN total NNAL and 2- / 3-HPMA in human urine

    PLOMLEY J.
    Altasciences, Laval, Canada
    Differential Ion Mobility Spectrometry (DMS) has recently emerged as an orthogonal gas-phase ion separation technique which, when interfaced between liquid chromatography (LC) and Tandem Mass Spectrometry (MS/MS), promises improvements in both assay ...
  5. CORESTA Meeting, Agronomy/Phytopathology, 2017, Santa Cruz do Sul, AP 04

    Contributions to the study of gall wasp occurrence in Eucalyptus woodlots in southern Brazil

    ROESCH F.(1); FEUERBORN M.(1); KOEHLER A.(2); RAUBER M.(2); FARIAS J.(3); WELTER C.A.(3); TEIXEIRA D.S.(3)
    (1) Japan Tobacco International (JTI), Santa Cruz do Sul, RS, Brazil; (2) Universidade de Santa Cruz do Sul (UNISC), Laboratory of Entomology, Santa Cruz do Sul, RS, Brazil; (3) Universidade Federal de Santa Maria (UFSM), Centro de Pesquisas Florestais, Campus Universitário, Santa Maria, RS, Brazil
    Firewood from Eucalyptus spp. is the main source of energy for tobacco curing in South Brazil. Leptocybe invasa Fisher & Lasalle, 2004 (Hymenoptera: Eulophidae) is a gall inducing wasp species that causes damage to eucalyptus plantations and nurseries ...
  6. CORESTA Meeting, Agronomy/Phytopathology, 2017, Santa Cruz do Sul, AP 49

    Potential alternative control for Ephestia spp. using parasitoid wasps

    KÖHLER A.(1); PEZZINI C.(1); ROESCH F.(2); FEUERBORN M.(2)
    (1) Universidade de Santa Cruz do Sul (UNISC), Laboratory of Entomology, Santa Cruz do Sul, RS, Brazil; (2) Japan Tobacco International (JTI), Santa Cruz do Sul, RS, Brazil
    Different practices are already used to control lepidopteran pests in stored tobacco, mostly including chemical or physical practices, preventive or disinfesting. Biological methods, used more frequently in tobacco field sites, are not used yet in stored ...
  7. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 21 (also presented at TSRC 2016)

    Puff-by-puff tar, nicotine and carbonyl profiles under different smoking regimens of commercial cigarettes with various carbon filter technologies

    ROBERTSON R.M.; NORFLEET K.; CANTERBURY W.B.
    Celanese, Narrows, VA, U.S.A.
    Puff-by-puff smoke analysis has shown that the CelFX ® carbon filter technology has similar nicotine and tar smoke delivery profiles but with significantly reduced carbonyls, particularly in the first 6 puffs, compared to a cellulose acetate filter. Prior ...