1. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, ST 20

    The influence of storage conditions and packaging on acetic acid generation in cellulose acetate fibers

    TATUM C.E.; WILSON S.A.; CASPER R.G.; PEARCE M.J.
    Eastman Chemical Company, Kingsport, TN, U.S.A.
    The cellulose acetate polymer used in cigarette filters is made by acetylating wood pulp with acetic anhydride. One advantage of this modified natural polymer is that it readily degrades by multiple mechanisms. While the ultimate products are carbon ...
  2. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 26

    A review of aerosol exposure systems relative to the analysis of cytotoxicity: a CORESTA In vitro Toxicity Testing Sub-Group perspective

    THORNE D.(1); WIECZOREK R.(2); FUKUSHIMA T.(3); SHIN H.J.(4); LEVERETTE R.(5); BALLANTYNE M.(6); LI X.(7); BOMBICK B.(5)
    (1) British American Tobacco, R&D Centre, Southampton, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (3) Japan Tobacco Inc., Scientific Product Assessment Centre, Yokohama, Kanagawa, Japan; (4) KT&G Corporation, Daejeon, South Korea; (5) RAI Services Company, Winston-Salem, NC, U.S.A.; (6) Covance Laboratories Ltd, Harrogate, U.K.; (7) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China
    Aerosol exposure systems offer researchers a variety of ways to customise the exposure set-up, modify experimental parameters and provide a novel and versatile platform for in vitro aerosol research. These systems produce an aerosol that more closely ...
  3. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 40

    Role of oxidative stress in the suppression of immune responses in peripheral blood mononuclear cells exposed to combustible tobacco product preparations

    PRASAD G.L.(1); ARIMILLI S.(2); DAMRATOSKI B.E.(2)
    (1) Scientific & Regulatory Affairs, RAI Services Company, Winston-Salem, U.S.A.; (2) Department of Microbiology & Immunology, Wake Forest University Health Sciences, U.S.A.
    Cigarette smoking is a major risk factor for several human diseases. Chronic inflammation, resulting from increased oxidative stress, has been suggested as a mechanism that contributes to the increased susceptibility of smokers to cancer and microbial ...
  4. TSRC, Tob. Sci. Res. Conf., 2016, 70, abstr. 17

    Ex vivo effects of smokeless tobacco extracts on select immune responses

    PRASAD G.L.(1); ARIMILLI S.(2); DAMRATOSKI B.E.(2); SCHMIDT E.(1); ROWE J.(3); CHOUCHANE S.(4)
    (1) RAI Services Company; (2) Wake Forest University Health Sciences; (3) R.J. Reynolds Tobacco Co.; (4) Eurofins Lancaster Labs Inc, Winston-Salem, NC, USA
    Our previous work demonstrated that exposure to Tobacco Product Preparations (TPPs) from combustible tobacco cause cytotoxic and select immunosuppressive effects in PBMCs, and this ex vivo model is well suited to investigate the chronic immune suppression ...