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107 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 27

    Next generation product aerosol bubbled extracts show little to no effect in high content screening endpoints when compared to cigarette smoke bubbled extracts

    TRELLES STICKEN E.(1); WIECZOREK R.(1); BODE L.M.(1); SIMMS L.(2); STEVENSON M.(2)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), BioToxLab, Hamburg, Germany; (2) Imperial Tobacco Limited, In vitro Research, Bristol, U.K.
    Tobacco-based and tobacco-free next generation products (NGPs) are understood to be a less harmful alternative to conventional combustible cigarettes. The objective of this study was to compare the in vitro biological response of cigarette smoke and a ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 34

    Next generation product aerosols induce lower biological activity than combusted cigarettes: a comparison of in vitro cell migration in the scratch wound assay

    RUDD K.(1); BUDDE J.(2); TRELLES STICKEN E.(2); WIECZOREK R.(2); SIMMS L.(1); STEVENSON M.(1)
    (1) Imperial Brands PLC, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    Smoking combustible cigarettes is a cause of serious diseases in smokers, including heart disease. There are many commercially available next generation products (NGPs), such as tobacco-free e-vapour products, aiming to provide an alternative to smoking ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 37

    Use of cell media nicotine concentration as a marker to predict cells surface deposited nicotine in transwells after fresh smoke/aerosol exposure

    WIECZOREK R.(1); TRELLES STICKEN E.(1); BODE L.M.(1); SIMMS l.(2)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (2) Imperial Tobacco Limited, Bristol, U.K.
    Exposure of organotypic 3D lung models at the air liquid interface (ALI) to fresh whole smoke/aerosol provides a more human relevant exposure assessment of combustible cigarettes and e-vapour products. The aim of this study is to present a method for ...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STW 01

    The application of in vitro Toxicity Testing in 21 Century (TT21C) for next generation products

    SIMMS L.(1); TRELLES STICKEN E.(2)
    (1) Imperial Brands PLC, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    The aim is to demonstrate the feasibility of TT21C in vitro methods as part of an overall assessment framework for next generation products (NGP). TT21C methodologies can be used to assess harm reduction potential of NGPs using human-derived cellular ...
  5. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 090

    Differential regulation of ion channel function from exposures to cigarette smoke and ENDs preparations

    RAYNER R.E.(1); MAKENA P.(2); PRASAD G.L.(2); CORMET-BOYAKA E.(1)
    (1) The Ohio State University, Columbus, OH, USA; (2) RAI Services Company, Winston Salem, NC, USA
    Cigarette smoking is known to disrupt the normal mucociliary function of the lungs, whereas the effect of Electronic Nicotine Delivery Systems (ENDS) is incompletely understood. This study aimed to compare the effects of acute exposure of primary normal ...
  6. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 39

    Impact of cigarette paper and blend on super slim, slim and king-size cigarette designs

    WANNA J.(1); CHEN Cai(2); XIAO Cuicui(3); LIANG Chenze(3); RUI Li(4); ZHANG Wenjun(4)
    (1) SWM Intl., Alpharetta, GA, U.S.A.; (2) SWM Shanghai Representative Office, Shanghai, P.R. China; (3) China Tobacco Mauduit, Jiangmen, Guangdong, P.R. China; (4) China Tobacco Schweitzer, Yuxi City, Yunnan, P.R. China
    Superslim (SS) cigarettes account for 5 % of total cigarette sales on the Chinese market, with a year to year increase of 2.1 %. Similar to this fast-growing trend, many more brands of slim (SL) cigarettes have been offered on the market since 2017. To ...
  7. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 47

    Study on reducing the fragmentation rate of paper-making reconstituted tobacco during the cutting process in the cigarette factory

    ZHANG Wenjun(1); TENNIER J.(2); TU Yangang(1); ZHANG Yan(3); ZHENG Jianyu(1); ZHANG Mengyuan(1); LI Rui(1); LIU Jing(1); XIONG Zhen(1); ZHOU Guiyuan(1)
    (1) China Tobacco Schweitzer (Yunnan) Reconstituted Tobacco Co., Ltd, Yuxi City, Yunnan, P.R. China; (2) SWM Intl., Alpharetta, GA, U.S.A.; (3) Yunnan Tobacco Quality Supervision and Inspection Station, Kunming, Yunnan, P.R. China
    It is known that reconstituted tobacco leaf tends to generate dust and particles during the cutting process in the cigarette factory. To solve the issue, analysis of the composition structure of manufacturing waste was carried out. Effects on the ...
  8. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 48

    Research on colour improvement of paper-making reconstituted tobacco

    SU Dandan(1); TU Yangang(1); ZHANG Wenjun(1); TENNIER J.(2); WEI Mingwen(1); WANG Xiaosheng(1); FENG Tao(1); MI Lan(1); ZHOU Guiyuan(1)
    (1) China Tobacco Schweitzer (Yunnan) Reconstituted Tobacco Co., Ltd, Yuxi City, Yunnan, P.R. China; (2) SWM Intl., Alpharetta, GA, U.S.A.
    Paper-making reconstituted tobacco (PRT) is an important raw material for the tobacco industry, with various benefits including reducing cost, smoke tar delivery, and impact on the environment. The different appearance of PRT compared to regular cigarette ...
  9. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 47

    Effect of ethanol concentration on chemical composition of tobacco extracts

    ZHENG Jianyu(1); LIU Changbo(1); ZHANG Wenjun(1); TENNIER J.(2); FU Yin(1); XIONG Zhen(1); CHEN Shaoquan(1); FENG Tao(1); WANG Yanhong(1); ZHOU Guiyuan(1)
    (1) China Tobacco Schweitzer (Yunnan) Reconstituted Tobacco Co., Ltd, Yuxi City, Yunnan, P.R. China; (2) SWM Intl., Alpharetta, GA, U.S.A.
    Ethanol is widely used as a solvent in the chemical, pharmaceutical, and biological industries, for the extraction of various natural products, including those from tobacco. In this study, an ethanol-water system with four different concentrations of ...
  10. CORESTA Congress, Berlin, 2016, Agronomy/Phytopathology Groups, APPOST 26

    Crop compliance: crop protection agents testing programme within purchases

    BODE L.M.; EVANS W.; INTORP M.
    Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    In order to ensure the compliance of our products, leaf grade purchases are monitored for the presence of any residual crop protection agents (CPA). CPA residue levels are first assessed for compliance against limits set by regulatory authorities and ...