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294 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 12

    Molecular mechanism involved in maleic hydrazide-mediated sucker control

    SHEN Y.; PAYAWULA R.; GOVINDURAJULU R.; KUDITHIPUDI C.; XU D.
    Altria Client Services LLC, Product Design & Maintenance, Richmond, VA, U.S.A.
    Molecular signals from the shoot apical meristem (SAM) mediate a hormonal signal that effectively inhibits axillary bud growth. Upon removal of the SAM, the hormonal signal is lost and enables axillary buds to grow into new shoots (or “suckers”) resulting ...
  2. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 35

    Genetic mapping and characterization of the pale yellow (Py) locus responsible for accelerated senescence in dark tobacco

    PRAMOD S.; ADAMS A.; DAVIS G.; LUSSO M.; FREDERICK J.; XU D.
    Altria Client Services LLC, Product Design & Maintenance, Richmond, VA, U.S.A.
    In commercial dark tobacco varieties (Nicotiana tabacum L.), accelerated senescence trait not only helps reduce TSNAs that are otherwise accumulated during the yellowing process associated with traditional dark varieties but also, could benefit growers in ...
  3. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 49 (also presented at TSRC 2019)

    Nicotine variability of low nicotine cultivars versus normal nicotine cultivars

    LION K.; ADAMS A.; MORRIS W.; BROWN E.; IRVING B.; LUSSO M.; XU D.
    Altria Client Services LLC, Product Design & Maintenance, Richmond, VA, U.S.A.
    Nicotine is the most abundant alkaloid in cultivated tobacco (Nicotiana tabacum), typically constituting more than 90 % of total alkaloids. Recently, the U.S. Food and Drug Administration (FDA) issued an Advance Notice of Proposed Rulemaking (ANPRM) to ...
  4. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 51

    Genetic and biochemical analysis of very low nicotine tobacco leaf

    KUDITHIPUDI C.(1); GOVINDARAJULU R.(2); BHUIYAN N.(2); SHEN Y.(1); XU D.(1)
    (1) Altria Client Services LLC, VA 23219, U.S.A.; (2) Eurofins Lancaster Laboratories, c/o Altria Client Services LLC, Richmond, VA, U.S.A.
    Recently, the U.S. Food and Drug Administration issued an advance notice of proposed rulemaking to obtain information for consideration in developing a tobacco product standard to set the maximum nicotine level in cigarette filler. Tobacco industry and ...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 13

    Importance of e-liquid preparation and stability characterization for a combinatorial safety assessment approach of flavors in e-liquids

    GLABASNIA A.(1); DIANA P.(1); SMITH C.(2); MILLER J.H.(2); BIASIOLI M.(1); FRAUENDORFER F.(1); SCIUSCIO D.(1); MARTIN E.(1); POSPISIL P.(1); GUY P.(1); VANSCHEEUWIJCK P.(1); HOENG J.(1); KUMAR A.(2); LEE K.M.(2)
    (1) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (2) Altria Client Services LLC, Richmond, VA, U.S.A.
    Numerous flavorings are generally recognized as safe for use in food, but there is limited information available to evaluate their potential toxicity by inhalation. Consequently, gaining information on individual flavor safety levels is of significant ...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 36 (also presented at TSRC 2019)

    HPHC market map study for U.S. machine-made cigars – Part 1: Physical properties, filler and smoke HPHC variability

    WAGNER K.A.; MORTON M.J.; OLEGARIO R.M.; BAKER L.L.; SMITH J.H.
    Altria Client Services LLC, Richmond, VA 23219, U.S.A.
    Market map studies have been used in the cigarette industry for many years to aid in the characterization of the marketplace. These studies provide comparative values and predictive models for aiding in the assessment of other products. However, the ...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 37 (also presented at TSRC 2019)

    HPHC market map study for U.S. machine-made cigars – Part 2: Predictive models

    MORTON M.J.; WAGNER K.A.; OLEGARIO R.M.; BAKER L.L.; SMITH J.H.
    Altria Client Services LLC, Richmond, VA 23219, U.S.A.
    Market map studies have been used in the cigarette industry for many years to aid in the characterization of the marketplace. These studies provide comparative values and predictive models for aiding in the assessment of other products. However, the ...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 38 (also presented at TSRC 2019)

    Optimized method for determination of selective phenolic compounds in cigarette and cigar smoke by UHPLC-FLD

    JIN X.C.; HURST T.J.; WAGNER T.J.
    Altria Client Services, Research, Development & Regulatory Affairs, Richmond, VA, U.S.A.
    Phenolic compounds, including phenol, catechol, and o-, m-, and p-cresol are included in the “Established List of the Chemicals and Chemical Compounds Identified by the FDA as Harmful and Potentially Harmful Constituents [HPHCs] in Tobacco Products and ...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 44

    Lung biomarkers of harm/effect for tobacco regulatory research: opportunities and challenges – a literature review

    MAKENA P.(1); EDMISTON J.(2); BEATTIE E.(3); MASON E.(4); McEWAN M.(5); PRASAD K.(5)
    (1) RAI Services Company, Winston-Salem, NC, U.S.A.; (2) Altria Client Services LLC, Richmond, VA, U.S.A.; (3) Cliantha Research Limited, Canada; (4) Imperial Brands PLC, Bristol, U.K.; (5) British American Tobacco (Investments) Limited, Southampton, U.K.
    Biomarkers of potential harm (BoPH) are indicators of biological perturbations in response to smoking, which may contribute to smoking-related disease. In this review, a project of the CORESTA Biomarkers Sub-Group, we critically assessed the available ...
  10. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 45

    Meta-analysis of two biomarkers of exposure of tobacco products

    AYALA-FIERRO F.(1); ELAMIN A.(2); FROST-PINEDA K.(3); JIN T.(3); PRASAD G.L.(3); SARKAR M.(4); SCHMIDT E.(3); VERRON T.(5)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (3) RAI Services Company, Winston-Salem, NC, U.S.A.; (4) Altria Client Services LLC, Richmond, VA, U.S.A.; (5) SEITA - Imperial Brands, Paris, France
    In the context of tobacco products, broadly two types of biomarkers exist, biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH). BoE measure exposure to tobacco constituents, e.g. carbon monoxide (CO) and nicotine equivalents (NEQs). The ...