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3 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2015, Jeju, STPOST 26

    Characterization of an electronic device that heats tobacco using an in vivo rodent inhalation exposure system

    BAKER G.(1); GUPTA A.(1); HAYDEN B.(1); SEKINE T.(2); SAKIMURA M.(3); LEE K.M.(4)
    (1) Battelle, W. Jefferson, OH, U.S.A.; (2) Japan Tobacco Inc., SPAC, Yokohama, Kanagawa, Japan; (3) Japan Tobacco Inc., CSRA, Tokyo, Japan; (4) JT International SA, Geneva, Switzerland
    Devices that heat, rather than combust tobacco, have been reported to deliver an aerosol which is chemically and biologically less complex than cigarette smoke. In this study, a nose-only inhalation exposure system was constructed for an electronic...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 41

    Activation of transcription factors in human bronchial epithelial cells exposed to aqueous extracts of mainstream cigarette smoke in vitro

    SEKINE T.; HIRATA T.; MINE T.; FUKANO Y.
    Japan Tobacco Inc., Product Science Division, R&D Group, Yokohama, Japan
    Transcription factors are recognised as important components of signalling cascades controlling all types of normal cellular processes as well as response to external stimulus. Activation of transcription factors can alter the expression of specific...