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3 results

  1. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 04

    Report on biological researches using a heated cigarette. Part 4: In vitro oxidative stress assays

    SUZUKI H.; NISHIJIMA Y.; FUKANO Y.
    Japan Tobacco Inc., R&D Group, Product Science Division, Yokohama, Kanagawa, Japan
    Mainstream cigarette smoke (MCS) is a mixture of several thousand constituents and is reported to include many oxidants, such as reactive oxygen species (ROS). ROS induced oxidative damage at molecular and cellular levels. At the 2010 CORESTA...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2011, Graz, ST 33

    An induction process for 8-hydroxy-2'deoxyguanosine (8-OHdG) induced by aqueous extracts of mainstream cigarette smoke in cultured cells

    NISHIJIMA Y.; FUKANO Y.
    Product Science Division, Japan Tobacco Inc., Yokohama, Kanagawa, Japan
    Oxidative stress is a state of imbalance between the reactive oxygen species (ROS) and the ability of the organism to defend against them, leading to progressive oxidative damage.8-hydroxy-2'deoxyguanosine (8-OHdG) is one of the markers for oxidative...
  3. CORESTA Congress, Edinburgh, 2010, SSPT 41

    The role of of cigarette smoke constituents in oxidative modification by aqueous extracts of mainstream cigarette smoke (part I) 8-OhdG

    NISHIJIMA Y.; FUKANO Y.
    Japan Tobacco Inc., R&D Group, Product Science Division, Yokohama, Kanagawa, Japan
    Oxidative stress is a state of imbalance between reactive oxygen species (ROS), and the ability of the organism to defend against them, leading to progressive oxidative damage. ROS causes oxidation of proteins, DNA and lipids, which may cause direct...