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61 results

  1. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 75

    Impacts of total particulate matter from cigarette smoke on early development of Zebrafish (Danio rerio)

    PRASAD G.L.(1); MASSARSKY A.(2); JAYASUNDARA N.(2).; DIGIULIO R.T.(2); BAILEY J.(3); LEVIN E.(3)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA; (2) Duke University, Durham, NC USA; (3) Duke University Medical Center, Durham, NC USA
    Cigarette smoke has been associated with a number of pathologies; however mechanisms leading to developmental effects are yet to be fully understood. This study examined the effects of Total Particulate Matter (TPM) from 3R4F reference cigarettes on...
  2. TSRC, Tob. Sci. Res. Conf., 2013, 67, abstr. 28

    The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces mitochondrial and nuclear DNA damage in Caenorhabditis elegans.

    PRASAD G.L.(1); BODHICHARLA R.(2); MEYER J.N.(2).
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA; (2) Duke University, Durham, NC, USA
    The metabolites of the tobacco-specific nitrosamine NNK form DNA adducts in animal models. A previous report indicates that NNK could cause damage to the mitochondrial as well as nuclear genome in rats (Stepanov and Hecht, 2009 Chem. Res. Toxicol....
  3. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SS 05

    Evaluation of a panel of potential gene biomarkers in two in vitro lung models following exposure to tobacco smoke and extracts

    FIELDS W.R.(1,2); LIEDTKE W.(2); LI J.(2); BOMBICK B.R.(1)
    (1) R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA; (2) Integrated Toxicology and Environmental Health Program, Duke University, Durham, NC 27710, USA
    Lung cells are frequently used in in vitro studies to assess the impact of cigarette smoke on defense and repair mechanisms of the lung. Previously, we identified a panel of fifteen genes representing inflammation, oxidative stress, metabolism and...
  4. CORESTA Congress, Kyoto, 2004, A 02

    Decision support system for soil fertility and water quality - evaluation in FCV tobacco- growing zones of India

    KRISHNAMURTHY V.; RAVISANKAR H.; DEO SINGH K.
    Central Tobacco Research Institute (CTRI), Rajahmundry (A.P.) India
    Information Technology has become an integral part of our day-to-day life. In agriculture, computers are extensively used to disseminate the information on soils, water, climatic conditions, pest and disease management and one such information system...
  5. Bull. Spec. CORESTA Congress, Lisbon, 2000, p. 140, PPOST8

    Bio-intensive integrated management of budworm, Helicoverpa armigera in FCV tobacco

    SITARAMAIAH S.; GUNNESWARA RAO S.; RAMAPRASAD G.; SREEDHAR U.
    Central Tobacco Research Institute (CTRI), Rajahmundry (A.P.) India
    Tobacco budworm, Helicoverpa armigera , is one of the limiting factors in successful production of Flue Cured Virginia (FCV) tobacco in Andhra Pradesh, India. It infests the crop during the grand growth period and inflicts severe damage to the bud...
  6. Bull. Spec. CORESTA Congress, Lisbon, 2000, p. 97, A9

    Lowering the nicotine content of flue-cured tobacco cultivars in South Africa

    VAN TONDER C.S.M.; KRUGER J.; DIPPENAAR M.C.
    Tobacco and Cotton Research Institute, Soil and Crop Science Division, Rustenburg, South Africa
    The nicotine content of flue-cured tobacco produced in the RSA is determined by factors suchas soil fertility, climatic conditions and production practices. The nicotine content of the leaf cannot be reduced dramatically without a detrimental effect...