Search Results

9 results

  1. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 26

    Contribution of manufacturing to variability in cigarette constituent levels

    HANNA S.N.(1); MORGAN W.T.(2); ROWE J.M.(2); OGDEN M.W.(1)
    (1) RAI Services Company, Winston-Salem, NC, U.S.A.; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, U.S.A.
    A range of tobacco and smoke analytes in cigarettes is of current regulatory interest. Understanding and communicating the variability associated with measurement of those analytes will aid regulators in making science-based decisions. Tobacco and smoke ...
  2. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 91

    Quantitative risk assessment of cigarette products from the US market, 2012 and 2013

    MARANO K.M.(1); MORGAN W.T.(2); OGDEN M.W.(1); SWAUGER J.E.(1)
    (1) RAI Services Company, Winston-Salem, NC, U.S.A.; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, U.S.A.
    Quantitative risk assessment, including incremental lifetime cancer risk (ILCR) and hazard index (HI) calculations, was applied to 160 cigarette products marketed in the United States (US) in 2012 and 2013. ILCR and HI values, incorporating both estimates ...
  3. CORESTA Congress, Kyoto, 2004, SS 01

    Individual variations in cigarette mainstream smoke biomarkers of exposure

    DOOLITTLE D.J.; SMITH C.J.; MORTON M.J.; BOMBICK D.W.; BROWN B.G.; HEAVNER D.L.; MORGAN W.T.; OGDEN M.W.; ROBINSON J.H.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Biomarkers of tobacco smoke exposure were measured in urine and buccal cells from 56 smokers of full-flavor low 'tar' (FFLT) cigarettes to evaluate the degree of individual variation. Biomarkers were measured while each individual smoked their ...
  4. CORESTA Congress, Kyoto, 2004, SS 02

    Multiple measures of variability (Part 1): Experimental design and human smoking behavior endpoints

    ROBINSON J.H.; OGDEN M.W.; BORGERDING M.F.; BYRD G.D.; HEAVNER D.L.; MORGAN W.T.; STILES M.F.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Previous work from our laboratory presented at CORESTA has supported the view that smokers exhibit significant variability on a number of smoking behavior endpoints including puffing topography, human smoke yields, smoker inhalation patterns and nicotine ...
  5. CORESTA Congress, Kyoto, 2004, SS 03

    Multiple measures of variability (Part 2): A study of smoker yields based on cigarette filter analysis after smoking

    BORGERDING M.F.; BODNAR J.A.; COLLINS T.J.; MORGAN W.T.; DEBUSK S.M.; ROBINSON J.H.; HEAVNER D.L.; OGDEN M.W.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    A study of smoker yields has been conducted based on sixty-nine subjects smoking their usual brand. Study objectives were (a) to assess individual smoker yield variability within a day and between days, (b) to compare smoker yields when cigarettes are ...
  6. Bull. Spec. CORESTA Congress, Brighton, 1998, p. 166, ST17

    Cigarette smoke yields obtained using averaged human puffing profiles vs. actual human profiles: what do standardized machine yields really tell us?

    ROBINSON J.H.; EDWARDS D.W.; GUY T.; MORGAN W.T.; GROHS M.L.; STILES M.F.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    The standardized machine smoking regimen that has been used for decades to rank cigarette smoke yields has recently been challenged by some because it does not precisely predict each smoker’s individual intake of ‘tar’ and nicotine. Surprisingly, the ...
  7. Bull. Spec. CORESTA Congress, Yokohama, 1996, p. 97, APST2

    Environmental room human physiology study using fresh diluted sidestream cigarette smoke

    SMITH C.J.; BOMBICK D.W.; MCKARNS S.C.; MORGAN W.T.; DOOLITTLE D.J.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Twenty healthy "never-smoking" subjects (ten males and ten females, ages 21-50) participated in a five-day environmental chamber study to determine if exposure to a moderately high level of cigarette smoke would alter indices related to urinary ...