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2 results

  1. TSRC, Tob. Sci. Res. Conf., 2009, 63, abstr. 19

    Development of in-vivo mouse model for smoking-induced cardiovascular disease

    EL-MAHDY M.A.; JOHNSON W.; HEMANN C.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Inst., Columbus, OH, USA
    Animal models for cigarette smoke associated diseases are important for research studies of the mechanisms involved in disease pathogenesis. We have developed an exposure protocol that results in cardiovascular dysfunction in the exposed mice. Male...
  2. TSRC, Tob. Sci. Res. Conf., 2009, 63, abstr. 59

    Cigarette smoke exposure results in hypertension, leukocytespecific reactive oxygen species (ROS) generation, endothelial dysfunction, and cardiac hypertrophy in mice

    ZWEIER J.L.; HASSAN TALUKDER M.A.; JOHNSON W.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Inst., Columbus, OH, USA
    Background: Cigarette smoking is a major risk factor for atherosclerotic cardiovascular diseases. While the association between smoking and atherosclerosis is well-established, the underlying mechanisms are incompletely understood. We report an in...