Search Results

7 results

  1. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 024

    Validated method for the quantitative determination of carbonyls in electronic cigarette aerosol and liquid

    QIAN N.; WILKINS J.; SEAMANS A.; ADAMS C.J.; CHOUCHANE S.
    Eurofins Lancaster Laboratories, Winston-Salem, NC, USA
    Carbonyls are typically found in tobacco and cigarette smoke. The Food and Drug Administration have included carbonyls in the list of HPHC's in the recent draft guidance for premarket tobacco application for electronic nicotine delivery systems for ...
  2. TSRC, Tob. Sci. Res. Conf., 2016, 70, abstr. 38

    Analysis of TSNAs in nicotine used as a component in e-liquids

    MOLDOVEANU S.(1); ZHU J.(2); QIAN N.(2)
    (1) R.J. Reynolds Tobacco Co.; (2) Eurofins Lancaster Labs. Inc., Winston-Salem, NC, USA
    Purified nicotine is a component of the e-liquids used in electronic cigarettes. This nicotine is typically obtained from tobacco; thus, in addition to nicotine, it contains minor alkaloids and possibly trace levels of TSNAs. The analysis of TSNAs in pure ...
  3. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 73

    A versatile method for the analysis of tsnas in tobacco products and cigarette smoke by LC-MS-MS

    ZHU J.(1); QIAN N.(1); JONES S.(1); MOLDOVEANU S.C.(2)
    (1) Eurofins Lancaster Laboratories, Winston Salem, North Carolina, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    A versatile method for the analysis of TSNAs has been applied to different tobacco sample matrices such as tobacco filler, smokeless and raw tobacco materials, as well as cigarette smoke. The method used an HPLC separation on a Phenomenex Gemini C18 ...
  4. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 29

    Analysis of free amino acids in tobacco, and validation on the Agilent 6490 LC-MS-MS system

    ZHU J.(1); QIAN N.(1); WILKINS J.(1); MOLDOVEANU S.C.(2)
    (1) Eurofins Lancaster Laboratories, Winston Salem, North Carolina, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    The present study describes a number of improvements and changes performed on a LC-MS-MS method for the analysis of amino acids in tobacco which was initially developed using an Agilent 1200 HPLC and a Sciex API 5000 MS-MS, and has been previously ...
  5. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 64

    Sensitive method for the determination of acrylamide in tobacco filler and alternative tobacco products by UPLC-MS/MS

    CHENG T.; QIAN N.; DENNIS M.; MOLDOVEANU S.C.; GERARDI A.R. (presented by CHOUCHANE S.)
    Lancaster Laboratories Inc., Lancaster, PA, USA; (2)R. J. Reynolds Tobacco Co., WinstonSalem, NC, USA
    A sensitive method for the analysis of acrylamide in tobacco cut filler and various alternative tobacco products was developed, optimized and fully validated. The method LOD was 1 ng/ mL (S/N = 3.7) and LOQ was 2.5 ng/mL (S/N=10.5). The method had a ...