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3 results

  1. TSRC, Tob. Sci. Res. Conf., 2016, 70, abstr. 59

    Determination of nicotine and its metabolites in rat brain using microdialysis coupled with UHPLC-Q-Exactive high resolution mass spectroscopy

    MAO Jian; LU Binbin; LI Peng; LIU Junhui; ZHANG Wenjuan; HONG Guangfeng; HUO Xiankuan; SUN Shihao
    Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, China
    In order to accurately determine nicotine (Nic) and its metabolites in rat brain, a method of microdialysis coupled with ultra high performance iquid chromatography-high resolution quadrupole-Orbitrap (UHPLC-Q-Exactive) mass spectrometry was established. ...
  2. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 73

    A novel model mouth system for evaluation of in vitro release of nicotine and tobacco-specific nitrosamines from moist snuff.

    JIE ZHANG; PENG LI; YONGLI ZONG; SHIHAO SUN; YUBING SONG; JIANPING XIE
    Zhengzhou Tobacco Research Institute, Zhegzhou, Henan, P.R. China.
    It is critical to characterize the release of nicotine and tobacco-specific nitrosamines (TSNA) from smokeless tobacco products for safety evaluation and product quality control. A novel model mouth system for evaluating the in vitro nicotine and TSNA ...