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3 results

  1. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 014 (also presented at CORESTA 2018)

    Genotoxicity evaluation of tobacco and nicotine delivery products: Part 1. Mouse lymphoma assay

    LEVERETTE R.(1); BOMBICK B.(1); FOWLER K.(1); BREHENY D.(2); GACA M.(2); THORNE D.(2); CLEMENTS J.(3); LLOYD M.(3); McENANEY S.(3)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) British American Tobacco (Investments) Ltd., Southampton, UK; (3) Covance Laboratories Ltd, Harrogate, UK
    In vitro studies have been widely used to support the toxicological evaluation of chemicals and complex mixtures including cigarette smoke. In this study a variety of test matrices from different tobacco and nicotine delivery products was assessed against ...
  2. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 015 (also presented at CORESTA 2018)

    Genotoxicity evaluation of tobacco and nicotine delivery products: Part 2. In vitro micronucleus assay

    LEVERETTE R.(1); BOMBICK B.(1); FOWLER K.(1); BREHENY D.(2); GACA M.(2); THORNE D.(2); CLEMENTS J.(3); McENANEY S.(3); WHITWELL J.(3)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) British American Tobacco (Investments) Ltd., Southampton, UK; (3) Covance Laboratories Ltd, Harrogate, UK
    In vitro studies have been widely used to support toxicological evaluations of chemicals and complex mixtures including cigarette smoke. In this study a variety of test matrices from tobacco and nicotine delivery products were assessed against a 3R4F ...
  3. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 10

    Dosimetric assessment of whole smoke particulate deposition in vitro: a proposed common approach using quartz crystal microbalance technology.

    ADAMSON J.; THORNE D.; DALRYMPLE A.; MEREDITH C.; DILLON D.
    British American Tobacco, Southampton, UK
    There are a number of different smoking machines and exposure chamber combinations used by our industry to assess the toxicological impact of cigarette smoke in vitro. The amount of smoke delivered to cells within an in vitro exposure system can be ...