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6 results

  1. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 129 (also presented at CORESTA SSPT2017)

    A computational model to characterize the Vitrocell® cell exposure system for evaluation of aerosols

    CASTRO N.(1); ROSTAMI A.A.(1); OLDHAM M.J.(1); PITHAWALLA Y.B.(1); LUCCI F.(2); KUCZAJ A.(2)
    (1) Altria Client Services, Richmond, VA, USA; (2) Philip Morris International, Neuchâtel, Switzerland
    In vitro exposure systems can be used as tools for toxicological assessment of e-cigarette aerosols. The VITROCELL® exposure system is designed such that exposure of cell cultures to the aerosol occurs at the air/liquid interface, which is relevant to e ...
  2. TSRC, Tob. Sci. Res. Conf., 2016, 70, abstr. 20

    Evaluation of a biomarker of oxidative stress: the 8-iso prostaglandin F2α: prostaglandin F2α ratio in human plasma

    MILLER P.(1); NEWLAND K.(1); DZERK A.(1); FARMEN R.(1); TRAN C.T.(2); HAZIZA C.(2); PICAVET P.(2)
    (1) Celerion, Inc., Lincoln, NE, USA; (2) Philip Morris International, Neuchâtel, Switzerland
    F2-isoprostanes have been widely studied as biomarkers of oxidative stress for various indications, including smoking. Since both enzymatic biosynthesis and chemical lipid peroxidation can generate these biomarkers, there are various interpretations that ...
  3. TSRC, Tob. Sci. Res. Conf., 2016, 70, abstr. 62

    FTIR method for e-cigarette aerosol characterization

    RADTKE F.; SUSZ A.; MONNI R.; STOOP A.; VERBEECK J.; MAEDER S.
    Philip Morris International, Research & Development, Philip Morris Products S.A., Neuchâtel, Switzerland
    The global electronic cigarettes (e-cig) market and product variety is expected to continue growing over the next years. This growth is being accompanied with interest in methods to compare different products for many reasons, including potential future ...
  4. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 28

    CSEO – The cigarette smoke exposure ontology

    YOUNESI E.(1), COGGINS C.(2); ANSARI S.(3); HOENG J.(3); PEITSCH M.(3); HOFMANN-APITIUS M.(1)
    (1) Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany; (2) Carson Watts Consulting, King, NC, USA; (3) Philip Morris International R&D, Neuchâtel, Switzerland
    In the past years, significant progress has been made in the development and use of experimental settings for collection of massive and precise experimental data on tobacco exposure and the diseases induced by it. Despite the growing number of such data, ...
  5. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 37

    A review of the literature on the degree of "compensatory" smoking of low-delivery cigarettes

    COGGINS C.; DEMPSEY R.; ROEMER E.
    Carson Watts Consulting, King, NC, USA; Philip Morris International Management SA, Neuchâtel, Switzerland
    To review trends in measures of compensatory smoking behavior over time and by method of assessment.Introduction. An analysis of the papers published on "compensatory" smoking, observed when smokers switch to lower-yielding products from higher ...