Search Results

10 results

  1. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 057

    AKR1C1 as a biomarker for differentiating the biological effects of combustible from non-combustible tobacco products

    TRAN Q.T.(1); WOO S.(2); HENDERSON D.(2); GAO H.(3); ZACHARIAS W.(3); LIU G.(1); PRASAD G.L.(1)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Axio Research, Seattle, WA, USA; (3) University of Louisville School of Medicine, Louisville, KY, USA
    Smoking has been established as a major risk factor for developing oral squamous cell carcinoma (OSCC), but less attention has been paid to the effects of smokeless tobacco products. Our objective is to identify potential biomarkers to distinguish...
  2. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 49

    On-line real-time analysis of e-cigarette vapours and heat-not-burn tobacco products by photo-ionization mass spectrometry

    ZIMMERMANN R.(1); EHLERT S.(2); STREIBEL T.(1); HEIDE J.(1); WOLTER J.(1); WALTE A.(2)
    (1) University of Rostock, Germany; (2) Photonion GmbH, Schwerin, Germany
    Photo ionization time-of-flight mass spectrometry (PI-TOFMS) is an established technology for on-line, puff-resolved characterization of organic compounds in smoke of conventional cigarettes. Many toxicants, such as butadiene, acetaldehyde, phenol or...
  3. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 41

    Highly time-resolved two-dimensional mapping of the molecular combustion and pyrolysis product concentrations during a puff in a burning cigarette

    ZIMMERMANN R.(1); HERTZ-SCHÜNEMANN R.(1); STREIBEL T.(1); EHLERT S.(2); WALTE A.(2); LIU C.(3); McADAM K.(3)
    (1) University of Rostock, Rostock, Germany; (2) Photonion GmbH, Schwerin, Germany; (3) British American Tobacco, Southampton, UK
    Cigarette smoking is an extremely complex and dynamic chemical process. The gas phase chemistry of tobacco combustion in the tobacco voids and pores is difficult to address by conventional analytical methods. Recently photo ionisation mass...
  4. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 70

    On-line photo ionization mass spectrometry for characterization of smoke from e-cigarettes or heat-not-burn devices

    ZIMMERMANN R.(1); STREIBEL T.(1); HEIDE J.(1); HERTZ-SCHÜNEMANN R.(1); EHLERT S.(2); WALTE A.(2); LIU C.(3); McADAM K.(3)
    (1) University of Rostock, Rostock, Germany; (2) Photonion GmbH, Schwerin, Germany; (3) British American Tobacco, Southampton, UK
    Photoionization time of flight mass spectrometry (PI-TOFMS) is well suited for on-line characterization of tobacco smoke. Depending on the photoionization method (single photon ionization, SPI or resonance-enhanced multiphoton ionization, REMPI),...
  5. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 55

    This blunt is for you – the routine and detailed chemistries of blunts and blunt wraps

    LAUTERBACH J.H.(1); GRIMM D.A.(2)
    (1) Lauterbach & Associates, LLC, Macon, GA, USA; (2) Tulane University, New Orleans, LA, USA
    At the FDA’s February 29, 2012, meeting, Expanding the Research Base for Tobacco Product Regulation, a member of the audience asked FDA scientists about what they were going to do about blunts. Unfortunately the FDA scientists did not know much about...
  6. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 33

    Setting the record straight - a reply to GOODPASTER et al. - The real chemistry and toxicology of novel smokeless tobacco products.

    LAUTERBACH J.H.(1); GRIMM D.A.(2)
    (1) Lauterbach & Associates, LLC, Macon, GA, USA; (2) Coordinated Instrumentation Facility, Tulane University, New Orleans, LA, USA
    The assessment of the toxicological properties of contemporary and novel smokeless tobacco products (STP) on the US market can be challenging. The responses of the extracts of such products in common in vitro assays are generally marginal, if indeed,...
  7. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 52

    Puff-resolved on-line real-time analysis and quantification of tobacco smoke components by a commercial smoke profiler (smoking machine - photo-ionization TOF mass spectrometer system).

    ZIMMERMANN R.(1); ROSE N.(2); WALTE A.(3); SARAJI-BOZORGZAD M.(3); BENTE M.(3); GROEGER T.(4); ESCHNER M.(4)
    (1) University of Rostock, Germany; (2) Borgwaldt KC, Hamburg, Germany; (3) Photonion GmbH, Schwerin, Germany; (4) Helmholtz Zentrum, Mnchen, Germany
    Recently, laser based photo-ionization mass spectrometry has been successfully coupled to smoking machines, allowing the puff-resolved on-line analysis of volatile and semi-volatile tobacco smoke constituents[1]. The introduction of special...
  8. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 53

    Detection of the molecular composition of pyrolysis gases in thermal analysis (TA) using photo ionization tof mass spectrometry for Evolved Gas Analysis (EGA): instrumental set-up and first results on tobacco and cigarettes materials.

    ZIMMERMANN R.(1); SARAJI-BOZORGZAD M.(2); BENTE M.(2); WALTE A.(2); ESCHNER M.(3)
    (1) University of Rostock, Germany; (2) Photonion GmbH, Schwerin, Germany; (3) Helmholtz Zentrum Mnchen, Germany
    Evolved Gas Analysis (EGA) in Thermogravimetry (TG) by mass spectrometry (MS) is a powerful technology for analysis of thermal degradation products from organic materials such as polymers, bio mass, paper or tobacco. TG-MS with electron ionization...
  9. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 29

    Use of two GC-MS scan techniques for the characterization of wrappers and binders taken from cigar products

    LAUTERBACH J.H.(1); GRIMM D.A.(2)
    (1) Lauterbach & Associates, LLC, Macon, GA, USA; (2) Coordinated Instrumentation Facility, Tulane University, New Orleans, LA, USA
    The proper classification of tobacco products is very important for regulatory and taxation purposes. Cigars products present a special problem because of the wide variation in sizes, blends, and additives used in the tobacco filler, and the nature...