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5 results

  1. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 002 (Symposium)

    The role of industry in engaging with industry to develop regulatory-approved methods for tobacco and nicotine product assessment

    PROCTOR C.J.; FEARON I.M.; MARINER D.C.; WRIGHT C.; MURPHY J.
    British American Tobacco (Investments) Limited, Southampton, UK
    Industry consensus methods for product assessment are commonplace across many industrial sectors and often form the basis of regulatory approaches. In the pharmaceutical industry for example, the foundations for the assessment of the safety, quality and ...
  2. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 106

    A study to examine changes in exposure to cigarette smoke chemicals when a smoker switches to using a tobacco heating product. Part I: study design

    GALE N.(1); McEWAN M.(1); ELDRIDGE A.(1); CAMACHO O.M.(1); McAUGHEY J.(1); MURPHY J.(1); LIU C.(1); PROCTOR C.J.(1); FEARON I.M.(1); SHERWOOD N.(2); BOWEN E.(3); McDERMOTT S.(3); HOLMES E.(3)
    (1) British American Tobacco (Investments) Ltd, Southampton, UK; (2) Neil Sherwood Consulting, Commugny, Switzerland; (3) Covance, Leeds, UK
    A tobacco heating product (THP), glo™, which heats rather than combusts tobacco and produces significantly reduced machine yields of chemical toxicants compared to combustible cigarettes, was assessed in this study. Biomarker of exposure (BoE) studies are ...
  3. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 107

    A study to examine changes in exposure to cigarette smoke chemicals when a smoker switches to using a tobacco heating product. Part II: study findings

    GALE N.(1); ELDRIDGE A.(1); McEWAN M.(1); ERRINGTON G.(1); MURPHY J.(1); PROCTOR C.J.(1); FEARON I.M.(1); McDERMOTT S.(2); GLEW J.(2); HEDGE A.(2)
    (1) British American Tobacco (Investments) Ltd, Southampton, UK; (2) Covance, Leeds, U.K.
    A tobacco heating product (THP), glo™, which heats rather than combusts tobacco and produces significantly reduced machine yields of chemical toxicants compared to combustible cigarettes, was assessed in this study. Biomarker of exposure (BoE) studies are ...
  4. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 17

    The use of cigarette smoke dilution by glycerol as a means of reducing smokers exposure to smoke toxicants.

    McADAM K.G.(1); GREGG E.O.(2); LIU C.(1); DITTRICH D.J.(1); DUKE M.G.(1); PROCTOR C.J.(1)
    (1) British American Tobacco, Group R&D, Southampton, UK; (2) Consultant, ENI Limited, Towcester, UK
    The Institute of Medicine encouraged the pursuit and development of potential reduced exposure products, tobacco products that substantially reduce exposure to one or more tobacco toxicants and can reasonably be expected to reduce the risk of one or more ...
  5. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 42

    Clinical studies to investigate the influence of reduced toxicant prototype cigarettes on levels of biomarkers of exposure and biological effect in healthy smokers.

    SHEPPERD J.; ELDRIDGE A.C.; McADAM K.; PROCTOR C.J.
    British American Tobacco, GR&D, Southampton, UK
    We have conducted a study that addresses the first part of the IOM's definition of a PREP by analyzing biomarkers of exposure (BoE) in smokers switched to prototype cigarettes which produced lower levels of some smoke toxicants compared to ...