1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 50 (also presented at TSRC 2019)

    Altered lung barrier function is a physiologically-relevant biomarker of potential harm

    MAKENA P.; BAXTER-WRIGHT S.; CHEN P.; PRASAD G.L.
    RAI Services Company, Winston Salem, NC, U.S.A.
    Cigarette smoking is a major risk factor for diseases including cardiovascular disease, lung cancer, and chronic obstructive pulmonary disease (COPD). One of the key functions of lung epithelial cells is to serve as a physical barrier against insults...
  2. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 015

    Levels of endothelial progenitor cells (EPCs) in smokers and moist snuff consumers

    ARIMILLI S.(1); CHEN P.(2); PRASAD G.L.(2)
    (1) Eurofins Professional Scientific Services, Winston Salem, NC, USA; (2) RAI Services Company, Winston Salem, NC, USA
    Endothelial progenitor cells (EPCs) are a key cell type present in circulation and are reported to play a role in the development of cardiovascular diseases. EPCs are derived from the bone marrow and mediate the differentiation, regeneration and...
  3. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 084 (also presented at CORESTA SSPT2019)

    Altered lung barrier function is a physiologically-relevant biomarker of potential harm

    MAKENA P.; BAXTER-WRIGHT S.; CHEN P.; PRASAD G.L.
    RAI Services Company, Winston Salem, NC, USA
    Cigarette smoking is a major risk factor for diseases including cardiovascular disease, lung cancer, and COPD. One of the key functions of lung epithelial cells is to serve as a physical barrier against insults including cigarette smoke. Chronic...
  4. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 091

    Tobacco-specific nitrosamines in the mainstream smoke of commercial little cigars

    EDWARDS S.H.(1); HASSINK M.(1); TAYLOR K.M.(1); WATSON C.(2); KUKLENYIK P.(2); WANG R.(2); CHEN P.(2); VALENTIN-BLASINI L.(2); KIMBRELL B.(2)
    (1) US Food and Drug Administration (FDA), Silver Spring, MD, USA; (2) Centers for Disease Control and Prevention, Atlanta, GA, USA
    Cigars are among the broad variety of deemed tobacco products that have been less extensively studied and characterized than cigarettes. Small sheet-wrapped cigars, often called little cigars, are a subcategory of cigars that are similar to...