Ann. Tabac, 1991, Sect. 1-20, p. 65-78., ISSN.0399-0206
Evaluation of the sensory irritation potential of cigarette smoke using the Alarie
SEITA, Centre de Recherche, Fleury les Aubrais, France
The stimulation of sensorial receptors by irritants induces, in small rodents, a decrease of respiratory frequency which is proportionnal to the agent concentration (Alarie test). This test is proposed for the evaluation of the irritant effect of ...