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10 results

  1. Beitr. Tabakforsch. Int., 1997, 17-3, p. 75-95., ISSN.0173-783X

    The role of amino acids and sugars in the production of volatile materials in microwave heated tobacco dust suspensions

    COLEMAN W.M. III; PERFETTI T.A.
    R.J. Reynolds Tobacco Company, Winston Salem, NC, USA
    For the first time, the role(s) of selected amino acids and sugars in the production of volatile compounds in microwave prepared heat treated tobacco suspensions (HTTS) has been unambiguously defined. The role can be expressed in two major reaction ...
  2. Beitr. Tabakforsch. Int., 1998, 18-1, p. 15-33., ISSN.0173-783X

    Chiral gas chromatography-selected ion monitoring-mass selective detection analysis of tobacco materials and tobacco smoke

    PERFETTI T.A.; COLEMAN W.M. III
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    A novel method for the detection, separation, and quantification of the optical isomers of nicotine has been developed. The method has been applied to analyze extracts of tobacco seeds, processed tobacco suspensions, reconstituted tobacco sheet materials, ...
  3. Beitr. Tabakforsch. Int., 1998, 18-1, p. 35-42., ISSN.0173-783X

    Chiral gas chromatography-selected ion monitoring-mass selective detection analysis of secondary alkaloids in tobacco and tobacco smoke

    PERFETTI T.A.; COLEMAN W.M. III
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Chiral gas chromatography-mass selective detection has been successfully employed in the analysis of secondary alkaloids in selected tobacco, materials and cigarette smoke condensate. No extensive sample preparation is involved. A lower detection limit of ...
  4. Bull. Spec. CORESTA Congress, Brighton, 1998, p. 166, ST17

    Cigarette smoke yields obtained using averaged human puffing profiles vs. actual human profiles: what do standardized machine yields really tell us?

    ROBINSON J.H.; EDWARDS D.W.; GUY T.; MORGAN W.T.; GROHS M.L.; STILES M.F.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    The standardized machine smoking regimen that has been used for decades to rank cigarette smoke yields has recently been challenged by some because it does not precisely predict each smoker’s individual intake of ‘tar’ and nicotine. Surprisingly, the ...
  5. Bull. Spec. CORESTA Congress, Brighton, 1998, p. 169, ST21

    The inhibitory effect of cotinine or cigarette smoke on the formation of O<sup>6</sup>-methylguanine adducts in the lung and liver of A/J mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

    DOOLITTLE D.J.; BROWN B.G.; AYRES P.H.; CHANG C.J.G.
    R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
    4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific nitrosamine, induces lung adenomas in A/J mice following a single intraperitoneal (i.p.) injection. NNK-induced lung tumorigenesis is thought to involve O 6-methylguanine (O 6 MeG) ...
  6. Bull. Spec. CORESTA Congress, Brighton, 1998, p. 70, APST3

    Massachusetts regulation regarding cigarette nicotine yield ratings - A summary of 1997 testing results

    BORGERDING M.F.; NORMAN V.; PANNELL W.T.; WHIDBY J.F.
    R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    On December 15, 1997, U.S. cigarette manufacturers provided the Commonwealth of Massachusetts with the first test results required under the Commonwealth's new cigarette testing law. These data included information on cigarette brand families sold in ...