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  1. CORESTA Meeting, Smoke Science/Product Technology, Stratford-upon-Avon, 2005, IG 01,CORESTA Meeting, Agronomy/Phytopathology, Santa Cruz do Sul, 2005, IG 02

    A new system for measuring the toxicity of mainstream cigarette smoke

    GAҪA M.D.; PHILLIPS J.; THORNE D.; LOWE F.; WILSON J.; MCEWAN M.; RICHTER A.; MASSEY E.D.
    British American Tobacco, Group R&D, Southampton, UK
    Cigarette smoke is a complex mixture of thousands of chemicals distributed between the particulate or 'tar' phase and the vapour phase which constitute 5% and 95% of whole smoke by weight, respectively. Historically, the in vitro toxicological ...
  2. CORESTA Meeting, Smoke Science/Product Technology, Stratford-upon-Avon, 2005, SSPT 22

    Development of an in vitro assay for the investigation of oxidative DNA damage induced by cigarette smoke

    McEWAN M.; THORNE D.; LOWE F.; WILSON J.; PHILLIPS J.; RICHTER A.; MASSEY E.D.
    British American Tobacco, Group R&D, Southampton, UK
    Cigarette smoke contains a mixture of more than 4,000 chemicals, some of which may be involved in oxidative damage of biomolecules, including DNA (Pourcelot et al. 1999). As a method of investigating these potential effects on DNA, the modified in vitro ...