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  1. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, CROM 00

    Science starts with measurement: essential measurement science for self-report in tobacco and nicotine product research

    McCAFFREY(1); MOREAN M.(2); AFOLALU E.(3); BLACK R.(1); SHIFFMAN S.(4); SARKAR M.(5)
    (1) Juul Labs Inc., Washington DC, U.S.A.; (2) Yale School of Medicine, New Haven, CT, U.S.A.; (3) Philip Morris Products S.A., Neuchatel, Switzerland; (4) Pinney Associates, Inc., Bethesda, MD, U.S.A.; (5) Altria Client Services LLC, Richmond, VA, U.S.A.
    Consumer reported outcome measures (CROM) are a critical component of tobacco regulatory science. Examples of CROM include measures of tobacco product dependence and risk perceptions. Like other fields of science, behavioral researchers require...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, CROM 05

    An illustration that one size may not fit all: assessing invariance of the WISDM scale in PATH across youth and young adult cohorts

    BLACK R.A.(1); SHIFFMAN S.(2); HANNON M.J.(2)
    (1) Juul Labs, Inc., Washington, DC, U.S.A.; (2) Pinney Associates, Inc., Pittsburgh, PA, U.S.A.
    Measuring dependence on ENDS in youth and adults is of interest, as dependence bears on continued use of such products. Dependence is an abstract, complex concept whose measurement can be highly context-specific. Typically, different scales are used...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, CROM 06

    Can individuals with limited health numeracy use quantitative scales to make ratings of risk perceptions?

    SHIFFMAN S.(1); HANNON M.J.(1); McCAFFREY S.(2)
    (1) Pinney Associates, Inc., Pittsburgh, PA, U.S.A.; (2) Juul Labs, Inc., Washington, DC, U.S.A
    Assessment of risk perceptions of lower-risk nicotine products such as electronic nicotine delivery systems (ENDS) is an important area of regulatory research. Psychometric challenges emerge when attempting to estimate and quantify their risk...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, ST 24

    Comparing adult smokers who switched to JUUL vs continuing smokers: biomarkers of exposure, biomarkers of potential harm and respiratory symptoms

    SHIFFMAN S.(1); OLIVERI D.R.(2); GOLDENSON N.I.(2); LIANG Qiwei(2); BLACK R.A.(2); MISHRA S.(2)
    (1) Pinney Associates, Inc., Pittsburgh, PA, U.S.A.; (2) Juul Labs, Inc., Washington, DC, U.S.A
    Assessment of biomarkers of exposure (BOEs) and biomarkers of potential harm (BOPHs) is an important way to inform the likely health impact of ENDS on users’ health. Observations in long-term users in real-world contexts are particularly important,...
  5. TSRC, Tob. Sci. Res. Conf., 2023, 76, abstr. 115

    Switching away from cigarettes across 24 months among us adult smokers who purchased the JUUL system

    GOLDENSON N.(1); SHIFFMAN S.(2); LE G.M.(1); BLACK R.A.(1)
    (1) Juul Labs, Inc., Washington, DC, USA; (2) Pinney Associates, Pittsburgh, PA, USA
    Evidence strongly suggests that electronic nicotine delivery systems (ENDS), while not without risk, are less harmful than combustible cigarettes. Accordingly, adult cigarette smokers who switch to ENDS likely benefit their individual health, and...
  6. TSRC, Tob. Sci. Res. Conf., 2023, 76, abstr. 116

    Comparing adult smokers who switched to JUUL vs continuing smokers: biomarkers of exposure and of potential harm and respiratory symptoms

    SHIFFMAN S.(1); OLIVERI D.R.(2); GOLDENSON N.I.(2); LIANG Qiwei(2); BLACK R.A.(2); MISHRA S.(2)
    (1) Pinney Associates, Bethesda, MD, USA; (2) Juul Labs, Inc., Washington, DC, USA
    More research on the effects of long-term switching in real-world contexts is needed to complement existing evidence from short-term randomized studies that switching from cigarette smoking to ENDS reduces toxicant exposures, and also extends to...
  7. TSRC, Tob. Sci. Res. Conf., 2023, 76, abstr. 39

    Analyzing the relationships between topography, e-liquid usage, and pharmacokinetics in JUUL2 prototype devices

    LIANG Qiwei(1); RIMMER L.(1); CHIEN J.(1); GOLDENSON N.(1); BLACK R.(1); SHIFFMAN S.(2); OLIVERI D.(3)
    (1) Juul Labs, Inc., Washington, DC, USA; (2) Pinney Associates, Bethesda, MD, USA; (3) Independent Consultant
    The latest JUUL2 prototypes come equipped with a new feature that enables it to record puffing typography parameters during product use. In a recent pharmacokinetic study involving 37 participants, two new prototype products were tested under both ad...