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  1. TSRC, Tob. Sci. Res. Conf., 2022, 75, abstr. 107

    Assessing the US population health impact of introducing a new e-cigarette product to market using intentions to use data

    VERRON T.; GUO Mengran; NAHDE T.; O’CONNEL G.; CAHOURS X.
    Imperial Brands, Bristol, UK
    In the absence of epidemiological data, computational models are valuable tools for predicting the likely impact of introducing a new tobacco / nicotine product to market on population health. Using best modeling practices, we have developed and...
  2. TSRC, Tob. Sci. Res. Conf., 2022, 75, abstr. 39

    Perceptions of the relative harm of electronic cigarettes compared with combustible cigarettes in the USA: analysis of the population assessment of tobacco and health (PATH) study data, 2013-2019

    CAHOURS X.; GUO Mengran; VERRON T.; O’CONNELL G.
    Imperial Brands, Bristol, UK
    Electronic cigarettes (e-cigarettes) have been acknowledged as having the potential to be substantially less harmful than smoked tobacco by an increasing number of public health authorities. Despite this, U.S. adults remain poorly informed about the...
  3. CORESTA Meeting, Agronomy/Phytopathology, 2021, Online, AP 08

    An update to the molecular markers used for rapid screening of pathogen resistant plants

    JULIO E.(1); COTUCHEAU J.(1); VOLPATTI R.(1); DECORPS C.(1); VERRON T.(2); CAHOURS X.(2); DORLHAC DE BORNE F.(1)
    (1) Imperial Brands, Leaf Research, Bergerac, France; (2) Imperial Brands, Scientific Research, Paris, France
    Due to cheaper costs associated with next generation sequencing (NGS) technologies, the availability of transcriptomic and genomic information has enabled the characterization of new molecular markers related to important agronomic traits. Today,...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 45

    Meta-analysis study to establish population level estimates of NNAL in smokers and non-smokers

    AYALA-FIERRO F.(1); VERRON T.(2); LIZHNYAK P.(3); FREELAND R.(4); FROST-PINEDA K.(4); ELAMIN A.(5); PRASAD G.L.(4); SARKAR M.(3)
    (1) Juul Labs, Inc, U.S.A.; (2) Imperial Brands, U.K.; (3) Altria Client Services, U.S.A.; (4) RAI Services Company, U.S.A.; (5) Philips Morris International, Switzerland
    The purpose of this research (a project of the CORESTA Biomarkers Sub-Group) was to establish a population level estimate for the biomarker of cigarette smoke exposure, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), to serve as a baseline...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 46

    Reductions in biomarkers of exposure to selected harmful and potentially harmful constituents following complete or partial transition to myblu™ ENDS (exclusive or dual use) compared to continued combustible cigarette smoking

    MORRIS P.(1); McDERMOTT S.(2); CHAPMAN F.(2); VERRON T.(2); CAHOURS X.(2); STEVENSON M.(2); THOMPSON J.(2); CHAUDHARY N.(2,a); O’CONNELL G.(2)
    (1) Nerudia Ltd - an Imperial Brands PLC Company, Speke, Liverpool, U.K.; (2) Imperial Brands PLC, Bristol, U.K.; (3) Broughton Nicotine Services, Earby, Lancashire, U.K.
    E-cigarettes offer an alternative, potentially reduced harm, method of nicotine delivery to adult combustible cigarette (CC) smokers, with harm reduction attributed to reduced levels of harmful or potentially harmful constituents (HPHCs) in their...
  7. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 30

    Examination of the impact of e-liquid nicotine strength on perceived dependence on myblu ENDS

    FEARON I.M.(1); SELTZER R.G.N.(2); HOUSER T.L.(2); NIDES M.(2); TOPE A.(3); CAHOURS X.(3); VERRON T.(3)
    (1) whatIF? Consulting Ltd, Harwell, UK; (2) LA Clinical Trials, Burbank, CA, USA (3) Imperial Brands, Bristol, UK
    Electronic nicotine delivery systems (ENDS) are a potentially less harmful alternative to combustible cigarette smoking for adult smokers. While it has been proposed that ENDS that have nicotine delivery characteristics similar to that of combustible...
  8. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 51

    An analysis of the 2020 us national youth tobacco survey (NYTS) data: e-cigarette and blu brand use among middle and high school students

    GUO Mengran; VERRON T.; CAHOURS X.; TOPE A.; O’CONNELL G.
    Imperial Brands PLC, 121 Winterstoke Road, Bristol, BS3 2LL, UK
    Youth use of nicotine containing products remains an important concern and understanding patterns of youth use over time is key to the design and implementation of comprehensive youth access and prevention programs. Electronic cigarettes (ENDS) are...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 45

    Meta-analysis of two biomarkers of exposure of tobacco products

    AYALA-FIERRO F.(1); ELAMIN A.(2); FROST-PINEDA K.(3); JIN T.(3); PRASAD G.L.(3); SARKAR M.(4); SCHMIDT E.(3); VERRON T.(5)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (3) RAI Services Company, Winston-Salem, NC, U.S.A.; (4) Altria Client Services LLC, Richmond, VA, U.S.A.; (5) SEITA - Imperial Brands, Paris, France
    In the context of tobacco products, broadly two types of biomarkers exist, biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH). BoE measure exposure to tobacco constituents, e.g. carbon monoxide (CO) and nicotine equivalents (NEQs)....
  10. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 56

    Perceptions of the relative harm of electronic cigarettes compared with smoking in the U.S.A.: analysis of the Population Assessment of Tobacco and Health (PATH) study data, 2013-2016

    O’CONNELL G.(1); WALELE T.(1); CAHOURS X.(2); THOMPSON J.(1); VERRON T.(2)
    (1) Imperial Tobacco Limited, Bristol, U.K.; (2) SEITA - Imperial Brands, Paris, France
    Electronic cigarettes (e-cigarettes) have been characterised as significantly less harmful than smoked tobacco by an increasing number of public health authorities. Despite this, U.S. adults remain poorly informed about the relative risk of these...