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13 results

  1. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 014

    Analysis of isotopically labeled glycerol to measure exposure from e-cigarettes

    DIBBERN E.M.; KAFONEK C.J.; BROWN G.P.; DZERK A.M.; NACHI R.; NEWLAND K.E.; ISLAM R. (presented by Erika Pfaumiller)
    Celerion, Lincoln, NE, USA
    Electronic cigarettes (ecigs) have become a popular mode of nicotine ingestion. They are often promoted as being less harmful than traditional cigarettes, but research supporting that claim is incomplete. The main chemical components of ecigs are...
  2. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 72

    The analysis of isotopically labeled propylene glycol in e-cigarettes

    FARMEN R.H.; NEWLAND K.E.; NACHI R.; KAFONEK C.J.; ISLAM R.
    Celerion, Lincoln, NE 68502 U.S.A. & Celerion, Zürich, Switzerland
    Measurement of the excipients in e-cigarettes has become a hot topic of discussion with the release of the new draft guidance from the United States Food and Drug Administration (FDA). However difficulties in the selective measurement of the...
  3. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 15

    A comparison of two methods for the quantification of tobacco-specific nitrosamines in human urine

    MILLER P.S.; DZERK A.M.; BROWN G.P.; NACHI R.; KAFONEK C.J.; NEWLAND K.E.
    Celerion, Lincoln, Nebraska, USA
    A validated method for the determination of four tobacco-specific nitrosamines (TSNAs) – NNAL, NNN, NAT, and NAB – was compared to a method published in 2009 in the Journal of Chromatography B 877: 1185-1192, by Kavvadias, Scherer, et al. Single sets...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 22

    The statistical benefit of performing GLP bioanalysis using assays that have reduced variability

    FARMEN R.H.; NEWLAND K.E.; GRAFF D.W.; COMBS M.L.
    Celerion, Lincoln, NE, U.S.A.; Celerion, Zürich, Switzerland
    Since the tobacco industry is moving into the area of regulated bioanalysis, we have noted that there is confusion surrounding the type of regulatory standards required for analytical methods to be used for testing tobacco constituents and biomarkers...