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  1. TSRC, Tob. Sci. Res. Conf., 2022, 75, abstr. 39

    Perceptions of the relative harm of electronic cigarettes compared with combustible cigarettes in the USA: analysis of the population assessment of tobacco and health (PATH) study data, 2013-2019

    CAHOURS X.; GUO Mengran; VERRON T.; O’CONNELL G.
    Imperial Brands, Bristol, UK
    Electronic cigarettes (e-cigarettes) have been acknowledged as having the potential to be substantially less harmful than smoked tobacco by an increasing number of public health authorities. Despite this, U.S. adults remain poorly informed about the...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 04

    Risk perceptions and likelihood of use of (tobacco-free oral) nicotine pouches among current, former and never nicotine users

    STONE C.; KNIGHT-WEST O.; O’CONNELL G.; TOPE A.
    Imperial Brands PLC, Research and Development, Bristol, U.K.
    Nicotine pouches deliver nicotine to the blood via the oral mucosa; since they are not combusted and contain no tobacco leaf, they have the potential to be significantly less harmful than continued combustible cigarette smoking. There is limited data...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 05

    Assessing the impact of next generation products on population health: a population modelling approach

    PHILLIPS C.V.(1); KHAKWANI A.(2); O’CONNELL G.(2); CAHOURS X.(2); TOPE A.(2)
    (1) epiphi Consulting Group, New Hampshire, U.S.A.; (2) Imperial Brands PLC., Bristol, U.K.
    Next Generation Products (NGPs) collectively represent novel nicotine-containing products that offer potentially reduced exposure to toxicants, toxicity and health risks to adult smokers compared to continued combustible cigarette smoking. To assess...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 46

    Reductions in biomarkers of exposure to selected harmful and potentially harmful constituents following complete or partial transition to myblu™ ENDS (exclusive or dual use) compared to continued combustible cigarette smoking

    MORRIS P.(1); McDERMOTT S.(2); CHAPMAN F.(2); VERRON T.(2); CAHOURS X.(2); STEVENSON M.(2); THOMPSON J.(2); CHAUDHARY N.(2,a); O’CONNELL G.(2)
    (1) Nerudia Ltd - an Imperial Brands PLC Company, Speke, Liverpool, U.K.; (2) Imperial Brands PLC, Bristol, U.K.; (3) Broughton Nicotine Services, Earby, Lancashire, U.K.
    E-cigarettes offer an alternative, potentially reduced harm, method of nicotine delivery to adult combustible cigarette (CC) smokers, with harm reduction attributed to reduced levels of harmful or potentially harmful constituents (HPHCs) in their...
  5. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 51

    An analysis of the 2020 us national youth tobacco survey (NYTS) data: e-cigarette and blu brand use among middle and high school students

    GUO Mengran; VERRON T.; CAHOURS X.; TOPE A.; O’CONNELL G.
    Imperial Brands PLC, 121 Winterstoke Road, Bristol, BS3 2LL, UK
    Youth use of nicotine containing products remains an important concern and understanding patterns of youth use over time is key to the design and implementation of comprehensive youth access and prevention programs. Electronic cigarettes (ENDS) are...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 56

    Perceptions of the relative harm of electronic cigarettes compared with smoking in the U.S.A.: analysis of the Population Assessment of Tobacco and Health (PATH) study data, 2013-2016

    O’CONNELL G.(1); WALELE T.(1); CAHOURS X.(2); THOMPSON J.(1); VERRON T.(2)
    (1) Imperial Tobacco Limited, Bristol, U.K.; (2) SEITA - Imperial Brands, Paris, France
    Electronic cigarettes (e-cigarettes) have been characterised as significantly less harmful than smoked tobacco by an increasing number of public health authorities. Despite this, U.S. adults remain poorly informed about the relative risk of these...
  7. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, ST 04

    Reduction of harmful or potentially harmful constituents (HPHCs) following partial or complete substitution of cigarettes with electronic cigarettes in adult smokers

    D’RUIZ C.D.(1); O’CONNELL G.(2); GRAFF D.W.(3)
    (1) Scientific Affairs Consultant, Fontem Ventures, B.V., Greensboro, NC, U.S.A.; (2) Fontem Ventures, B.V., Scientific and Regulatory Affairs, Amsterdam, The Netherlands; (3) Celerion, Lincoln, NE, U.S.A.
    Changes in fifteen urine, blood, and exhaled breath biomarkers of exposure (BoE) to harmful and potentially harmful constituents (HPHCs), representing major classes of compounds reported by the FDA to be significant contributors to smoking-associated...
  8. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, ST 42

    Exhaled aerosol properties in a room following use of electronic cigarettes and conventional cigarettes

    CAHOURS X.(1); MARTUZEVICIUS D.(2); PRASAUSKAS T.(2); SETYAN A.(3,4); O’CONNELL G.(5); JULIEN R.(1); WANG J.(3,4); COLARD S.(1)
    (1) SEITA-Imperial Tobacco, Fleury-les-Aubrais, France; (2) Department of Environmental Technology, Kaunas University of Technology, Kaunas, Lithuania; (3) Laboratory for Advanced Analytical Technologies, EMPA (Swiss Federal Laboratories for Materials Science and Technology), Dübendorf, Switzerland; (4) Institute of Environmental Engineering, ETH Zürich, Zürich, Switzerland; (5) Fontem Ventures B.V., HN Amsterdam, Netherlands
    Use of electronic cigarettes (e-cigarettes) is rapidly increasing among smokers as an alternative to conventional tobacco cigarettes (CC). As e-cigarettes do not contain tobacco and do not require combustion, the mechanism of aerosol generation...
  9. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 18

    Assessment of the so-called “gateway effect” based on electronic vapour product classifications

    VERRON T.(1); CAHOURS X.(1); CERSON L.(2); COLARD S.(1); O’CONNELL G.(3)
    (1) SEITA-Imperial Tobacco, Fleury-les-Aubrais, France; (2) Imperial Tobacco Limited, Bristol, U.K.; (3) Fontem Ventures B.V., Amsterdam, Netherlands
    Since electronic cigarettes (e-cigs) became popular as alternatives to conventional cigarettes, with subsequent market growth amongst smokers, there is currently a debate as to whether e-cigs may be a "gateway" to conventional cigarette smoking or...
  10. TSRC, Tob. Sci. Res. Conf., 2016, 70, abstr. 23

    Reductions in biomarkers of exposure (BoE) to harmful or potentially harmful constituents (HPHCs) following partial or complete substitution of cigarettes with electronic cigarettes in adult smokers

    O’CONNELL G.(1); GRAFF D.W.(2); D’RUIZ C.(3)
    (1) Fontem Ventures B.V, Amsterdam, The Netherlands; (2) Celerion Inc, Lincoln, NE, USA; (3) Fontem Ventures B.V Greensboro, NC, USA
    Changes in fifteen urine, blood and exhaled breath BoEs of HPHCs representing classes of compounds reported by FDA to be significant contributors to smoking-associated disease risks were measured in 105 clinical-confined subjects following...