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19 results

  1. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 05 (also presented at TSRC 2018)

    Structure-activity relationships of propylene glycol, glycerin, and select analogs for carbonyl thermal degradation products

    MELVIN M.S.; BALLENTINE R.M.; GARDNER W.P.; McKINNEY W.J.; PITHAWALLA Y.B.; SMITH D.C.; WAGNER K.A.
    Altria Client Services LLC, Richmond, VA, U.S.A.
    In 2016, the Food and Drug Administration (FDA) issued draft Guidance to Industry regarding the submission of Premarket Tobacco Applications for electronic nicotine delivery systems (ENDS). In this draft guidance, the FDA recommends reporting several ...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 07 (also presented at TSRC 2018)

    Evaluation of the formaldehyde hemiacetals and acetals relevant to electronic cigarettes

    JIN Xiaohong C.; AVERY K.C.; BALLENTINE R.M.; GARDNER W.P.; McKINNEY W.J.; MELVIN M.S.; PITHAWALLA Y.B.; SMITH D.C.; WAGNER K.A.
    Altria Client Services LLC, Richmond, VA, U.S.A.
    In 2016, the Food and Drug Administration (FDA) issued draft Guidance to Industry regarding the submission of Premarket Tobacco Applications for Electronic Nicotine Delivery Systems (ENDS). In this draft guidance, the FDA recommends reporting toxicants in ...
  3. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 24 (also presented at TSRC 2018)

    Temporal variability of analytical testing for e-vapor products and impact on number of replicates

    MORTON M.J.; GARDNER W.P.; AGNEW-HEARD K.A.; MILLER IV J.H.
    Altria Client Services LLC, Richmond, VA, U.S.A.
    In May 2016, the U.S. Food and Drug Administration (FDA) published a guide for industry “Premarket Tobacco Product Applications for Electronic Nicotine Delivery Systems.” Among other things the guidance document provided testing recommendations to support ...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 32

    Characterization and in vitro testing of whole smoke condensates from combustible cigarettes

    DOSHI U.(1); GARDNER W.P.(1); GILLMAN I.G.(2); LEE K.M.(1)
    (1) Altria Client Services LLC, Research, Development & Regulatory Affairs, Richmond, VA, U.S.A.; (2) Enthalpy Analytical, Inc., Richmond, VA, U.S.A.
    Health Canada recommends in vitro testing of separately collected gas and particulate phases of cigarette smoke for cytotoxicity and genotoxicity assessment. While these test materials have shown cytotoxicity and genotoxicity in literature, there has been ...
  5. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 44 (also presented at TSRC 2018)

    Non-targeted analysis using gas chromatography mass spectrometry to evaluate stability of e-vapor products

    SHAH N.; CROSSWHITE M.; NOE M.R.; SUAREZ C.; MILLER J.H.; PITHAWALLA Y.B.; GARDNER W.P.
    Altria Client Services LLC, Richmond, VA, U.S.A.
    In the newly regulated landscape of tobacco products there is an increasing need to fully characterize the chemical composition of aerosol in new products. Although aerosol from e-vapor products are considerably less complex than aerosols from heat-not ...
  6. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 064 (also presented at CORESTA 2018)

    Non-targeted analysis using gas chromatography mass spectrometry to evaluate stability of e-vapor products

    CROSSWHITE M.; SHAH N.; NOE M.; SUAREZ C.; MILLER J.H. IV; PITHAWALLA Y.B.; GARDNER W.P.
    Altria Client Services LLC, Richmond, VA, USA
    In the newly regulated landscape of tobacco products there is an increasing need to fully characterize the chemical composition of aerosol in new products. Although aerosol from e-vapor products are considerably less complex than aerosols from Heat-Not ...
  7. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 084 (also presented at CORESTA 2018)

    Evaluation of the formaldehyde hemiacetals and acetals relevant to electronic cigarettes

    JIN Xiaohong Cathy; AVERY K.C.; BALLENTINE R.M.; GARDNER W.P.; McKINNEY W.J.; MELVIN M.S.; PITHAWALLA Y.B.; SMITH D.C.; WAGNER K.A.
    Altria Client Services LLC, Richmond, VA, USA
    In 2016, the Food and Drug Administration (FDA) issued draft Guidance to Industry regarding the submission of Premarket Tobacco Applications for Electronic Nicotine Delivery Systems (ENDS). In this draft guidance, the FDA recommends reporting toxicants in ...
  8. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 087 (also presented at CORESTA 2018)

    Structure-activity relationships of propylene glycol, glycerin, and select analogs for carbonyl thermal degradation products

    MELVIN M.S.; BALLENTINE R.M.; GARDNER W.P.; McKINNEY W.J.; PITHAWALLA Y.B.; SMITH D.C.; WAGNER K.A.
    Altria Client Services LLC, Richmond, VA, USA
    In 2016, the Food and Drug Administration (FDA) issued draft Guidance to Industry regarding the submission of Premarket Tobacco Applications for Electronic Nicotine Delivery Systems. In this draft guidance, the FDA recommends reporting several carbonyl ...
  9. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 104 (also presented at CORESTA 2018)

    Temporal variability of analytical testing for e-vapor products and impact on number of replicates

    MORTON M.J.; GARDNER W.P.; AGNEW-HEARD K.A.; MILLER J.H. IV
    Altria Client Services LLC, Richmond, VA, USA
    In May 2016, the US Food and Drug Administration published a guide for industry “Premarket Tobacco Product Applications for Electronic Nicotine Delivery Systems.” Among other things the guidance document provided testing recommendations to support ...
  10. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 10

    Investigation of TSNA formation in electronic cigarette liquids and aerosols

    JIN X.C.; AVERY K.C.; GARDNER W.P.; KARLES G.D.; MELVIN M.S.; SMITH D.C.; McKINNEY W.J.; WAGNER K.A.
    Altria Client Services LLC, Richmond, VA, U.S.A.
    Electronic cigarette (e-cigarette) formulations typically contain tobacco derived nicotine and therefore, may contain other tobacco related components such as trace levels of tobacco specific nitrosamines (TSNAs), nitrite, and minor alkaloids. Previous ...